ID G4YW20_PHYSP Unreviewed; 515 AA.
AC G4YW20;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Aldehyde dehydrogenase {ECO:0000256|PIRNR:PIRNR036492};
GN ORFNames=PHYSODRAFT_556984 {ECO:0000313|EMBL:EGZ24403.1};
OS Phytophthora sojae (strain P6497) (Soybean stem and root rot agent)
OS (Phytophthora megasperma f. sp. glycines).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=1094619 {ECO:0000313|EMBL:EGZ24403.1, ECO:0000313|Proteomes:UP000002640};
RN [1] {ECO:0000313|EMBL:EGZ24403.1, ECO:0000313|Proteomes:UP000002640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P6497 {ECO:0000313|EMBL:EGZ24403.1,
RC ECO:0000313|Proteomes:UP000002640};
RX PubMed=16946064; DOI=10.1126/science.1128796;
RA Tyler B.M., Tripathy S., Zhang X., Dehal P., Jiang R.H., Aerts A.,
RA Arredondo F.D., Baxter L., Bensasson D., Beynon J.L., Chapman J.,
RA Damasceno C.M., Dorrance A.E., Dou D., Dickerman A.W., Dubchak I.L.,
RA Garbelotto M., Gijzen M., Gordon S.G., Govers F., Grunwald N.J., Huang W.,
RA Ivors K.L., Jones R.W., Kamoun S., Krampis K., Lamour K.H., Lee M.K.,
RA McDonald W.H., Medina M., Meijer H.J., Nordberg E.K., Maclean D.J.,
RA Ospina-Giraldo M.D., Morris P.F., Phuntumart V., Putnam N.H., Rash S.,
RA Rose J.K., Sakihama Y., Salamov A.A., Savidor A., Scheuring C.F.,
RA Smith B.M., Sobral B.W., Terry A., Torto-Alalibo T.A., Win J., Xu Z.,
RA Zhang H., Grigoriev I.V., Rokhsar D.S., Boore J.L.;
RT "Phytophthora genome sequences uncover evolutionary origins and mechanisms
RT of pathogenesis.";
RL Science 313:1261-1266(2006).
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|PIRNR:PIRNR036492,
CC ECO:0000256|RuleBase:RU003345}.
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DR EMBL; JH159152; EGZ24403.1; -; Genomic_DNA.
DR RefSeq; XP_009519691.1; XM_009521396.1.
DR AlphaFoldDB; G4YW20; -.
DR STRING; 1094619.G4YW20; -.
DR EnsemblProtists; EGZ24403; EGZ24403; PHYSODRAFT_556984.
DR GeneID; 20663202; -.
DR KEGG; psoj:PHYSODRAFT_556984; -.
DR InParanoid; G4YW20; -.
DR OMA; RRITWAA; -.
DR Proteomes; UP000002640; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0006081; P:cellular aldehyde metabolic process; IEA:InterPro.
DR CDD; cd07087; ALDH_F3-13-14_CALDH-like; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR012394; Aldehyde_DH_NAD(P).
DR PANTHER; PTHR43570; ALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR43570:SF16; ALDEHYDE DEHYDROGENASE TYPE III, ISOFORM Q; 1.
DR Pfam; PF00171; Aldedh; 1.
DR PIRSF; PIRSF036492; ALDH; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000256|PIRNR:PIRNR036492,
KW ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000002640};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 484..507
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 6..449
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT COILED 32..59
FT /evidence="ECO:0000256|SAM:Coils"
FT ACT_SITE 224
FT /evidence="ECO:0000256|PIRSR:PIRSR036492-1,
FT ECO:0000256|PROSITE-ProRule:PRU10007"
FT ACT_SITE 258
FT /evidence="ECO:0000256|PIRSR:PIRSR036492-1"
SQ SEQUENCE 515 AA; 56450 MW; 216E1656983EFC6A CRC64;
MADSTTRVPP TSAEAVASSV AALRASFRSG ATRDLKTRLA QLKQLRRMLA ENVRELQDAL
YHDLRKPPAE TLISELAPVR GEISLHEEEL EDWAAPERVW TNVANLPGRS YVQREPLGVV
CIMSTWNYPV QLSLWPLVGA ISAGNCVLLR LPSHDTCVHT SELLLKLVTS YMDPRFVRVV
HGGIPATQAA LAQKFDLILC TGGVTIGKIV AEAAAKTLTP TILELGGKSP TIVDETCDVA
VTARRITWAA FMNAGQTCLR PDYVLVSAKV GDELVAAIQR EIAAFFGEDA QKSASYGRLI
SPKAFDRAAA FLERDAEYVV FGGAKDREDQ FVAPTLLNFK KDVEAFTRSA VMQEEVLSPL
LPIVYYDSLD EAIDFVNERE KPLALYLYSS DYKVRTRVLA ETSSGSACVN DSIMQSVNMN
LPFGGVGSSG MGSYHGKYSF DAFSHKKSVL IKYALFDAPQ RYMPYTNSGL RIVLMLLKPL
PSSLIVLVAY AFISLGFVVM GLFLQIYRGG AVIEE
//
