ID   G5AAQ2_PHYSP            Unreviewed;       891 AA.
AC   G5AAQ2;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   03-MAY-2023, entry version 45.
DE   RecName: Full=PH domain-containing protein {ECO:0000259|PROSITE:PS50003};
GN   ORFNames=PHYSODRAFT_528193 {ECO:0000313|EMBL:EGZ07681.1};
OS   Phytophthora sojae (strain P6497) (Soybean stem and root rot agent)
OS   (Phytophthora megasperma f. sp. glycines).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=1094619 {ECO:0000313|EMBL:EGZ07681.1, ECO:0000313|Proteomes:UP000002640};
RN   [1] {ECO:0000313|EMBL:EGZ07681.1, ECO:0000313|Proteomes:UP000002640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=P6497 {ECO:0000313|EMBL:EGZ07681.1,
RC   ECO:0000313|Proteomes:UP000002640};
RX   PubMed=16946064; DOI=10.1126/science.1128796;
RA   Tyler B.M., Tripathy S., Zhang X., Dehal P., Jiang R.H., Aerts A.,
RA   Arredondo F.D., Baxter L., Bensasson D., Beynon J.L., Chapman J.,
RA   Damasceno C.M., Dorrance A.E., Dou D., Dickerman A.W., Dubchak I.L.,
RA   Garbelotto M., Gijzen M., Gordon S.G., Govers F., Grunwald N.J., Huang W.,
RA   Ivors K.L., Jones R.W., Kamoun S., Krampis K., Lamour K.H., Lee M.K.,
RA   McDonald W.H., Medina M., Meijer H.J., Nordberg E.K., Maclean D.J.,
RA   Ospina-Giraldo M.D., Morris P.F., Phuntumart V., Putnam N.H., Rash S.,
RA   Rose J.K., Sakihama Y., Salamov A.A., Savidor A., Scheuring C.F.,
RA   Smith B.M., Sobral B.W., Terry A., Torto-Alalibo T.A., Win J., Xu Z.,
RA   Zhang H., Grigoriev I.V., Rokhsar D.S., Boore J.L.;
RT   "Phytophthora genome sequences uncover evolutionary origins and mechanisms
RT   of pathogenesis.";
RL   Science 313:1261-1266(2006).
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DR   EMBL; JH159162; EGZ07681.1; -; Genomic_DNA.
DR   RefSeq; XP_009537247.1; XM_009538952.1.
DR   AlphaFoldDB; G5AAQ2; -.
DR   EnsemblProtists; EGZ07681; EGZ07681; PHYSODRAFT_528193.
DR   GeneID; 20661214; -.
DR   KEGG; psoj:PHYSODRAFT_528193; -.
DR   InParanoid; G5AAQ2; -.
DR   OMA; YPDVMEF; -.
DR   Proteomes; UP000002640; Unassembled WGS sequence.
DR   CDD; cd00821; PH; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR009769; EDR2_C.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   PANTHER; PTHR31558; CW14 PROTEIN; 1.
DR   PANTHER; PTHR31558:SF3; CW14 PROTEIN; 1.
DR   Pfam; PF07059; EDR2_C; 1.
DR   Pfam; PF00169; PH; 1.
DR   SMART; SM00233; PH; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002640}.
FT   DOMAIN          248..401
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   REGION          77..110
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          152..181
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          431..466
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          598..622
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        157..175
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        431..449
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:EGZ07681.1"
SQ   SEQUENCE   891 AA;  99288 MW;  0602174FB8950BAD CRC64;
     SNNGEGFIAE KDYLYLLNYL EEYMSLPKQL YAAFEECMIP MAGLLSNSQF VTWVRQYPDV
     MEFLAIHLPP SPLPGNPLNN SPSCRNDPNR NPFRSFDFIG GEDSGDEDSD GLYDSDQITE
     MEMSQSSFRD SSASLNGHDE LTSILKEAGA VVQDESGERS SDISVSSQRQ GRSGASRARG
     VQKMGRYMGK AVGGGISRVG NVGRSILHVG KSQGYNQHHI GDHPNDDPAA VELLSAGYSF
     SSESQSTKKY VCGYLHKISD SKWGKKRSWH RRWFVLDRQR GVLSYYRHNP ANHMPTSSAS
     HGNIVHMADS PQDQDHDPQQ TLLYLNESHP WYRGALDLNM DNVSLLFEKT LARNAPTRYF
     FQVSTLSLHD IDSKRGVQYK LCADTETDFD LWTSAIAEAI NRKDSQNGKA NSGAPVLSHQ
     QLYRQRLLQK QMEEEQAAKE REAEAANEAA ADSGHESPPP TLGRRKIPPR IVTQFSLGPD
     SGMPTDSCWH LHVHVDGTKQ CLIVGFMLNI VAIRCLASEH VLWKVAVCIA VTCMFVFSVY
     NPRSLVHRPR QASFGAYSDV NGGIDNALLG TDIAQCSDPE RCCLHKISSP TVLDRGDCDD
     NKRVEGSSDA PRRRPSAAGS RRLAKLPMGS TMTQCEMQTS GRSSNVEHSW TTTRAETFSV
     RSAEYKRSRK KEPSSAALFE FLGADLVRTD SKLDLISQRV EFPPEHENSR LFIINAQLPS
     YGPSMWGDGS YDGPGYSLAL YWKIPDEISE ELKNPTTTTL KLFKRFLEAG DDTSLTDRFK
     VIAQVTNQDE CGITGVAKKL LVSHNATPVL TRPQHRIYHF RDGSTEIVVD VHAFSYIARR
     GIHSLIDKTS KLVIDVAFVI QGETEEELPE RVLGCCRLDR VNVQKAVDLP C
//