ID G5AFJ2_PHYSP Unreviewed; 448 AA.
AC G5AFJ2;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Polycystin cation channel PKD1/PKD2 domain-containing protein {ECO:0000259|Pfam:PF08016};
DE Flags: Fragment;
GN ORFNames=PHYSODRAFT_450148 {ECO:0000313|EMBL:EGZ05982.1};
OS Phytophthora sojae (strain P6497) (Soybean stem and root rot agent)
OS (Phytophthora megasperma f. sp. glycines).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=1094619 {ECO:0000313|EMBL:EGZ05982.1, ECO:0000313|Proteomes:UP000002640};
RN [1] {ECO:0000313|EMBL:EGZ05982.1, ECO:0000313|Proteomes:UP000002640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P6497 {ECO:0000313|EMBL:EGZ05982.1,
RC ECO:0000313|Proteomes:UP000002640};
RX PubMed=16946064; DOI=10.1126/science.1128796;
RA Tyler B.M., Tripathy S., Zhang X., Dehal P., Jiang R.H., Aerts A.,
RA Arredondo F.D., Baxter L., Bensasson D., Beynon J.L., Chapman J.,
RA Damasceno C.M., Dorrance A.E., Dou D., Dickerman A.W., Dubchak I.L.,
RA Garbelotto M., Gijzen M., Gordon S.G., Govers F., Grunwald N.J., Huang W.,
RA Ivors K.L., Jones R.W., Kamoun S., Krampis K., Lamour K.H., Lee M.K.,
RA McDonald W.H., Medina M., Meijer H.J., Nordberg E.K., Maclean D.J.,
RA Ospina-Giraldo M.D., Morris P.F., Phuntumart V., Putnam N.H., Rash S.,
RA Rose J.K., Sakihama Y., Salamov A.A., Savidor A., Scheuring C.F.,
RA Smith B.M., Sobral B.W., Terry A., Torto-Alalibo T.A., Win J., Xu Z.,
RA Zhang H., Grigoriev I.V., Rokhsar D.S., Boore J.L.;
RT "Phytophthora genome sequences uncover evolutionary origins and mechanisms
RT of pathogenesis.";
RL Science 313:1261-1266(2006).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; JH159165; EGZ05982.1; -; Genomic_DNA.
DR RefSeq; XP_009538843.1; XM_009540548.1.
DR AlphaFoldDB; G5AFJ2; -.
DR EnsemblProtists; EGZ05982; EGZ05982; PHYSODRAFT_450148.
DR GeneID; 20652916; -.
DR KEGG; psoj:PHYSODRAFT_450148; -.
DR InParanoid; G5AFJ2; -.
DR OMA; SEDNWIN; -.
DR Proteomes; UP000002640; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR InterPro; IPR013122; PKD1_2_channel.
DR InterPro; IPR003915; PKD_2.
DR PANTHER; PTHR10877:SF183; AT14535P-RELATED; 1.
DR PANTHER; PTHR10877; POLYCYSTIN FAMILY MEMBER; 1.
DR Pfam; PF08016; PKD_channel; 1.
DR PRINTS; PR01433; POLYCYSTIN2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002640};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 222..243
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 290..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 335..358
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 398..421
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 286..424
FT /note="Polycystin cation channel PKD1/PKD2"
FT /evidence="ECO:0000259|Pfam:PF08016"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EGZ05982.1"
FT NON_TER 448
FT /evidence="ECO:0000313|EMBL:EGZ05982.1"
SQ SEQUENCE 448 AA; 49711 MW; B2034D68ABC1C590 CRC64;
VLFSHIPTSR MYAEAYSLSS VLASSGGDAV TASSPMKFSY IGQLSDVFDW LNNSLVPSVF
VTQDQNGFDL DSKDFARVGL FNKGLGGVII EVYRRTESDC APNTYLYDLY ETCHQGSITR
FSYILFFSLD ATEASQALDE WKSEDNWINN ATDRAVISVL TYNGELEGYV VTELTLTLDQ
GGFVTPTSLV RPTISIPYGS SSSYASDVLW RKKANRPSGR EMVLRLFSLF SVEVVLSVFY
VLWGTIVGLL NDPDFQDAIH NYADPFKADD VGETEGINAL LDVMGDLKTI AHYTAALRAV
GAVVTALLCL QILNRFRFHP QLNILTRTVA SALKQFGAFF VVFIVIFMGF AIIGSMIFGD
QAKEFSSLTN SMRSCINIIF GQFDLDCIED IPFSVVFFWG YMIVVGIVLL NLMLAIVLDA
YDQVSKESYK KASNLKLANR VISICYDV
//
