ID G5AJZ2_HETGA Unreviewed; 184 AA.
AC G5AJZ2;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Tumor necrosis factor alpha-induced protein 8-like protein 2 {ECO:0000256|ARBA:ARBA00039711};
GN Name=TNFAIP8L2 {ECO:0000313|EMBL:JAN96437.1};
GN ORFNames=GW7_10551 {ECO:0000313|EMBL:EHA97352.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHA97352.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHA97352.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
RN [2] {ECO:0000313|EMBL:JAN96437.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Skin {ECO:0000313|EMBL:JAN96437.1};
RA Bens M., Sahm A., Jahn N., Morhart M., Holtze S., Hildebrandt T.B.,
RA Platzer M., Szafranski K.;
RT "FRAMA: From RNA-seq data to annotated mRNA assemblies.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TNFAIP8 family. TNFAIP8L2 subfamily.
CC {ECO:0000256|ARBA:ARBA00038062}.
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DR EMBL; JH165545; EHA97352.1; -; Genomic_DNA.
DR EMBL; GEBF01007195; JAN96437.1; -; Transcribed_RNA.
DR RefSeq; XP_004854074.1; XM_004854017.2.
DR RefSeq; XP_004854075.1; XM_004854018.2.
DR AlphaFoldDB; G5AJZ2; -.
DR STRING; 10181.G5AJZ2; -.
DR Ensembl; ENSHGLT00100022781; ENSHGLP00100022547; ENSHGLG00100016581.
DR Ensembl; ENSHGLT00100056784; ENSHGLP00100036757; ENSHGLG00100016581.
DR Ensembl; ENSHGLT00100082717; ENSHGLP00100028928; ENSHGLG00100016581.
DR Ensembl; ENSHGLT00100089491; ENSHGLP00100058812; ENSHGLG00100016581.
DR GeneID; 101704834; -.
DR KEGG; hgl:101704834; -.
DR CTD; 79626; -.
DR eggNOG; ENOG502QST4; Eukaryota.
DR InParanoid; G5AJZ2; -.
DR OMA; IRRVFDH; -.
DR OrthoDB; 5401401at2759; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR Bgee; ENSHGLG00000005573; Expressed in zone of skin and 10 other cell types or tissues.
DR GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR Gene3D; 1.20.1440.160; Tumor necrosis factor alpha-induced protein 8-like; 1.
DR InterPro; IPR008477; TNFAIP8-like.
DR InterPro; IPR038355; TNFAIP8_sf.
DR PANTHER; PTHR12757:SF4; TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 8-LIKE PROTEIN 2; 1.
DR PANTHER; PTHR12757; TUMOR NECROSIS FACTOR INDUCED PROTEIN; 1.
DR Pfam; PF05527; DUF758; 1.
PE 3: Inferred from homology;
KW Immunity {ECO:0000256|ARBA:ARBA00022859};
KW Innate immunity {ECO:0000256|ARBA:ARBA00022588};
KW Reference proteome {ECO:0000313|Proteomes:UP000006813}.
SQ SEQUENCE 184 AA; 20618 MW; 620978241D629F65 CRC64;
MESFSSKSLA LQVEKKLLSK MAGRSVAHLF IDETSSEVLD ELYRVSKDYT HSRPQAQRVI
KDLVKVAVKV AVLHRNGCFG PEELALATRF RQKLRQGAMT ALSFGEVDFT FEAAVLAGLL
TECRDVLLEL VGRHLTPKSH GRIRHVFDHF SDLGLLTALY GPDFRQHLGK ICDGLRKLLD
EGKL
//
