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Database: UniProt
Entry: G5AYV8_HETGA
LinkDB: G5AYV8_HETGA
Original site: G5AYV8_HETGA 
ID   G5AYV8_HETGA            Unreviewed;      2156 AA.
AC   G5AYV8;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   10-MAY-2017, entry version 30.
DE   SubName: Full=Voltage-dependent T-type calcium channel subunit alpha-1I {ECO:0000313|EMBL:EHB02228.1};
GN   ORFNames=GW7_02605 {ECO:0000313|EMBL:EHB02228.1};
OS   Heterocephalus glaber (Naked mole rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
OC   Hystricomorpha; Bathyergidae; Heterocephalus.
OX   NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB02228.1, ECO:0000313|Proteomes:UP000006813};
RN   [1] {ECO:0000313|EMBL:EHB02228.1, ECO:0000313|Proteomes:UP000006813}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21993625; DOI=10.1038/nature10533;
RA   Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA   Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA   Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA   Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L.,
RA   Bronson R.T., Buffenstein R., Wang B., Han C., Li Q., Chen L.,
RA   Zhao W., Sunyaev S.R., Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT   "Genome sequencing reveals insights into physiology and longevity of
RT   the naked mole rat.";
RL   Nature 479:223-227(2011).
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DR   EMBL; JH167581; EHB02228.1; -; Genomic_DNA.
DR   InParanoid; G5AYV8; -.
DR   Proteomes; UP000006813; Unassembled WGS sequence.
DR   GO; GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro.
DR   GO; GO:0008332; F:low voltage-gated calcium channel activity; IEA:InterPro.
DR   GO; GO:0070509; P:calcium ion import; IEA:InterPro.
DR   GO; GO:0030317; P:flagellated sperm motility; IEA:InterPro.
DR   GO; GO:0019228; P:neuronal action potential; IEA:InterPro.
DR   InterPro; IPR030162; CACNA1I.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR005445; VDCC_T_a1.
DR   PANTHER; PTHR10037:SF258; PTHR10037:SF258; 1.
DR   Pfam; PF00520; Ion_trans; 4.
DR   PRINTS; PR01629; TVDCCALPHA1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000006813};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006813};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    153    172       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    240    264       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    377    398       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    404    429       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    794    817       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    838    857       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    877    901       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1209   1227       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1247   1268       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1280   1306       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1344   1366       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1445   1469       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1525   1542       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1562   1581       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1645   1672       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1747   1768       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      129    440       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      636    906       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     1207   1479       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     1525   1778       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   COILED     1478   1505       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   2156 AA;  238358 MW;  05E5A858D12E1350 CRC64;
     MRATLDDAFQ RIPVFTKTET FKESNADLAK PAASCLVLGA PGLSRLQVPQ GFLCGADMAE
     STSPPSSSAA AAPALEPGIT EQPGPQSPPP SPPGLEEPLD GADPDVPHPD LAPVAFFCLR
     QTTSPRNWCI KMPCDDMDCL SDRCKILQVF DDFIFIFFAM EMVLKMVALG IFGKKCYLGD
     TWNRLDFFIV MAGMVEYSLD LQNINLSAIR TVRVLRPLKA INRVPSMRIL VNLLLDTLPM
     LGNVLLLCFF VFFIFGIIGV QLWAGLLRNR CFLEENFTIQ GDMALPPYYQ PEEDDEIPFI
     CSLSGDNGIM GCHEIPPLKE QGRECCLSKD DVYDFGAGRQ DLNASGLCVN WNRYYNVCRT
     GSANPHKGAI NFDNIGYAWI VIFQVITLEG WVEIMYYVMD AHSFYNFIYF ILLIIVGSFF
     MINLCLVVIA TQFSETKQRE HRLMLEQRQR YLSSSTVASY AEPGDCYEEI FQYVCHILRK
     ARRRALGLYQ VLQSRHQALG LGAPAPAKPG PHAKEPRHCK LCLRHSPLDP TPHTLVQPIS
     AMLASDPISC PRCQHGTGQQ PSGPGSTDSG QEGSGSGGSG GDEVEADGDG PRSSEDGGSS
     GPGKEDEEEQ PDGAAGLCGD VWRETRGKLR GIVDSKYFNR GIMMAILVNT VSMGIEHHEQ
     ASVVGLQLGS SRSTGSIQFT QIRPPGLPLT LWLELLPEEL TNILEICNVV FTSMFALEMI
     LKLAAFGLFD YLRNPYNIFD SIIVIISIWE IVGQADGGLS VLRTFRLLRV LKLVRFMPAL
     RRQLVVLMKT MDNVATFCML LMLFIFIFSI LGMHIFGCKF SLRTDTGDTV PDRKNFDSLL
     WAIVTVFQAS GSSVSILTQE DWNVVLYNGM ASTSPWASLY FVALMTFGNY VLFNLLVAIL
     VEGFQAEGDA NRSYSDEDQS SSNMEELDKL QEGLDSSGDL KLCPIPMTPN GHLDPSLPLG
     GHLGPSGAAD PAARLSLQPD PMLVALDSRK SSVMSLGRMS YDQRSLSSSR SSYCGPWGRS
     GAWASRRSSW NSLKHKPPSA EHESLLSAER SGARVSEGAR DEGPPRAAPL HAPHVHHAHH
     GPHVAHRHRH HRRTLSLDTR DSVDLAELVP TVGGHPRAAW RAAGSGPGHE NCNGRMPSIA
     KDVFTKMDDR RDRGDDEEEI DYTLCFRVRK MIDVYKPDWC EIREDWSVYL FSPENRFRVL
     CQTVIAHKLF DYVVLAFIFL NCITIALERP QIEAGSTERI FLTVSNYIFT AIFVGEMTLK
     VVSLGLYFGE QAYLRSSWNV LDGFLVFVSI IDIVVSVASA GGAKILGVLR VLRLLRTLRP
     LRVISRAPGL KLVVETLISS LKPIGNIVLI CCAFFIIFGI LGVQLFKGKF YHCLGVDTRN
     ITNRSDCVAA NYRWVHHKYN FDNLGQALMS LFVLASKDGW VNIMYNGLDA VAVDQQPVTN
     HNPWMLLYFI SFLLIVSFFV LNMFVGVVVE NFHKCRQHQE AEEARRREEK RLRRLEKKRR
     KAQRLPYYAT YCPTRLLIHS MCTSHYLDIF ITFIICLNVV TMSLEHYNQP TSLETALKYC
     NYMFTTVFVL EAVLKLVAFG LRRFFKDRWN QLDLAIVLLS VMGITLEEIE INAALPINPT
     IIRIMRVLRI ARVLKLLKMA TGMRALLDTV VQALPQVGNL GLLFMLLFFI YAALGVELFG
     KLACNEENPC EGLSRHATFE NFGMAFLTLF QVSTGDNWNG IMKDTLRDCT HDERSCLSSL
     QFVSPLYFVS FVLTAQFVLI NVVVAVLMKH LDDSNKEAQE DAEMDAEIEL EMAHGLGPSP
     QPPAASPGAP GRGPGVAGSG GDSEGHRCRR CYSPAQETLW LDSVSLIIKD SLEGELTIID
     NLSGSIFHHY ASPTPAGCRK CHHDKQEVQL AETEAFSLNS DRSSSILLGD DLSLEDPTAC
     PSGPKDSKGE PDVSEPMRVG DLGECFFPLP NAAVSSGTEN FLCEMEAIPF NPVRSWLKHE
     SSQAPPSPFS PDSSSPLLPM PAEFFHPAVS TSQKGQEGGA GVGTLPKIAL QGSWASLRSP
     SVNCTLLRQA TVSDTSLDAS PSSSAGSLQT TLEDSLTLSD SPRCVLGPPA PVPGPRAGLS
     PATRAVSIEL YICVLYSLQF FKNYTTTQPR GLARRPSWAS DRSKDPTGQA TLSSGP
//
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