ID G5AYZ5_HETGA Unreviewed; 515 AA.
AC G5AYZ5;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 24-JAN-2024, entry version 65.
DE SubName: Full=Potassium voltage-gated channel subfamily G member 1 {ECO:0000313|EMBL:EHB02256.1};
GN ORFNames=GW7_16432 {ECO:0000313|EMBL:EHB02256.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB02256.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB02256.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; JH167583; EHB02256.1; -; Genomic_DNA.
DR RefSeq; XP_004858102.1; XM_004858045.2.
DR AlphaFoldDB; G5AYZ5; -.
DR STRING; 10181.G5AYZ5; -.
DR Ensembl; ENSHGLT00100010218; ENSHGLP00100010098; ENSHGLG00100007500.
DR GeneID; 101722608; -.
DR KEGG; hgl:101722608; -.
DR CTD; 3755; -.
DR eggNOG; KOG3713; Eukaryota.
DR InParanoid; G5AYZ5; -.
DR OMA; CAFRNIL; -.
DR OrthoDB; 1478695at2759; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR Bgee; ENSHGLG00000011040; Expressed in ovary and 2 other cell types or tissues.
DR GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:Ensembl.
DR GO; GO:0005251; F:delayed rectifier potassium channel activity; IEA:Ensembl.
DR GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR CDD; cd18421; BTB_POZ_KCNG1_2; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR003968; K_chnl_volt-dep_Kv.
DR InterPro; IPR003969; K_chnl_volt-dep_Kv6.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR003131; T1-type_BTB.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR11537:SF88; POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY G MEMBER 1; 1.
DR PANTHER; PTHR11537; VOLTAGE-GATED POTASSIUM CHANNEL; 1.
DR Pfam; PF02214; BTB_2; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR PRINTS; PR00169; KCHANNEL.
DR PRINTS; PR01492; KV6CHANNEL.
DR PRINTS; PR01491; KVCHANNEL.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Reference proteome {ECO:0000313|Proteomes:UP000006813};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882}.
FT TRANSMEM 301..319
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 378..399
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 411..428
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 440..461
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 64..173
FT /note="BTB"
FT /evidence="ECO:0000259|SMART:SM00225"
FT REGION 184..206
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 515 AA; 58123 MW; 5817F65A7C79790A CRC64;
MTLLPGDNSD YDYSALSCTS DASFHPAFFP QSQALKGVFY RRAQRLRPQD APHPGSPGPG
DRRRQIIINV GGIKYSLPWT TLDEFPMTRL GQLKACTNFD DILNVCDDYD VTCNEFFFDR
NPGAFGTILT FLRAGKLRLL REMCALSFQE ELLYWGIAED HLDRCCKRRY LQKIEEFAEM
VEREDEEDAL DSEARDSDGP ESGEGRLSRC MRRLRDMVER PHSGLPGKVF ACLSVLFVTV
TAVNLSVSTL PSLREEEEQG QCSQMCHNVF IVESVCVGWF SLEFLLRFIQ APSKFAFLRS
PLTLIDLVAI LPYYVTLMVD GAASGRRKPS SGNSYLDKVG LVLRVLRALR ILYVMRLARH
SLGLQTLGLT ARRCTREFGL LLLFLCVAIA LFAPLLYVIE NEMADSPEFT SIPACYWWAV
ITMTTVGYGD MVPRSTPGQV VALSSILSGI LLMAFPVTSI FHTFSRSYLE LKQEQERVMF
RRAQFLIKTK SQLSDMSQDS DILFGSASSD TRDKN
//
