ID G5B2F9_HETGA Unreviewed; 326 AA.
AC G5B2F9;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=ethanolamine kinase {ECO:0000256|ARBA:ARBA00038874};
DE EC=2.7.1.82 {ECO:0000256|ARBA:ARBA00038874};
DE Flags: Fragment;
GN ORFNames=GW7_00571 {ECO:0000313|EMBL:EHB03470.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB03470.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB03470.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- PATHWAY: Phospholipid metabolism; phosphatidylethanolamine
CC biosynthesis; phosphatidylethanolamine from ethanolamine: step 1/3.
CC {ECO:0000256|ARBA:ARBA00037883}.
CC -!- SIMILARITY: Belongs to the choline/ethanolamine kinase family.
CC {ECO:0000256|ARBA:ARBA00038211}.
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DR EMBL; JH168132; EHB03470.1; -; Genomic_DNA.
DR AlphaFoldDB; G5B2F9; -.
DR STRING; 10181.G5B2F9; -.
DR eggNOG; KOG2686; Eukaryota.
DR InParanoid; G5B2F9; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0046474; P:glycerophospholipid biosynthetic process; IEA:UniProt.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd05156; ChoK_euk; 1.
DR Gene3D; 3.90.1200.10; -; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR PANTHER; PTHR22603; CHOLINE/ETHANOALAMINE KINASE; 1.
DR PANTHER; PTHR22603:SF35; CHOLINE_ETHANOLAMINE KINASE; 1.
DR Pfam; PF01633; Choline_kinase; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000313|EMBL:EHB03470.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006813};
KW Transferase {ECO:0000313|EMBL:EHB03470.1}.
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EHB03470.1"
SQ SEQUENCE 326 AA; 38061 MW; AAC6F668DDAC55FE CRC64;
RVWVCSGGLS NLLFRCSLPN HLPNVGEEPR EVLLRLYGAI LQGVESLVLE SVMFAILAER
SLGPQLYGVF PEGRLEQYLP SRPLKTQELR KPVLSAAIAA KMARFHGMEM PFTKEPHWLF
GTMERYLKQI QDLPSATLLQ MDLLEMYSLQ DEMDNLRKLL ESTPSPVVFC HNDVQEGNIL
LLSEPENADS LMLVDFEYSS YNYRGFDIGN HFCEWVYNYT HEEWPFYKAQ PTDYPTREQQ
LHFIRHYLAE VKKGEILPQE EQNKLEEDLL VEANRYALAS HFFWGLWSIL QASMSTIEFG
YLEYAQSRFQ FYFQQKRQLT SFHSSS
//
