ID G5B368_HETGA Unreviewed; 529 AA.
AC G5B368;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Myosin-binding protein H {ECO:0000313|EMBL:EHB03729.1};
GN ORFNames=GW7_12847 {ECO:0000313|EMBL:EHB03729.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB03729.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB03729.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
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DR EMBL; JH168168; EHB03729.1; -; Genomic_DNA.
DR AlphaFoldDB; G5B368; -.
DR STRING; 10181.G5B368; -.
DR eggNOG; ENOG502QVIQ; Eukaryota.
DR InParanoid; G5B368; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR CDD; cd00063; FN3; 2.
DR CDD; cd05748; Ig_Titin_like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 4.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR14340; MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3; 1.
DR PANTHER; PTHR14340:SF9; TITIN; 1.
DR Pfam; PF00041; fn3; 2.
DR Pfam; PF07679; I-set; 2.
DR PRINTS; PR00014; FNTYPEIII.
DR SMART; SM00060; FN3; 2.
DR SMART; SM00409; IG; 2.
DR SMART; SM00408; IGc2; 2.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50853; FN3; 2.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 4: Predicted;
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Reference proteome {ECO:0000313|Proteomes:UP000006813};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 89..184
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 188..276
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 285..380
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 398..482
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 1..87
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..45
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 55..69
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 529 AA; 57249 MW; 41B943FBC4522435 CRC64;
MAGKATSEAP ASGRDETVPE SESAKVPTTG PSGEAAASES TGEEQAREPQ GPAAQAPAPT
APAPPVAPAA PEASAATKPA PASEDVPSSP LLLTVVDVSH NSVTVSWEPP ERLGRLGLQG
YMLEFCREGA SEWVPVTPRP MMVTQQTVRN LALGDKFLLR VAAVSSAGAG PPALLDQPVH
IQEIIEAPKI RVPRHLRQIY VRLVGESINL QIPFQGKPKP QASWTHNGQA LDSQRVSVRS
GDQDSILFIR SAQRSDSGCY ELTVRLEGLE AKATIDILVI ERPGPPKSIR VLDVWGCNAA
LEWTPPQDTG NTELLGYTVQ KADKKTGQWF TVLERYHPTT CTISDLIIGN SYSFRVFSEN
LCGLSDSATA TKELAHIRKA DITAKPQGFI ERDFSEAPSF TQPLADHTST PGYSTQLFCS
VRASPKPKII WMKNNMDIKG DPKYRALSEQ GICTLEIRKP SPFDSGIYTC KAVNVLGEAS
VDCRLEVKGE GLERVTPRIL PWMGGQKPLF GNWTRCRSEQ KTKAGEKGQ
//
