ID G5BE92_HETGA Unreviewed; 548 AA.
AC G5BE92;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Interferon-alpha/beta receptor beta chain {ECO:0000313|EMBL:EHB07603.1};
GN ORFNames=GW7_08743 {ECO:0000313|EMBL:EHB07603.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB07603.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB07603.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
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DR EMBL; JH169803; EHB07603.1; -; Genomic_DNA.
DR AlphaFoldDB; G5BE92; -.
DR STRING; 10181.G5BE92; -.
DR eggNOG; ENOG502S60E; Eukaryota.
DR InParanoid; G5BE92; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR015373; Interferon/interleukin_rcp_dom.
DR PANTHER; PTHR20859:SF84; INTERFERON ALPHA_BETA RECEPTOR 2; 1.
DR PANTHER; PTHR20859; INTERFERON/INTERLEUKIN RECEPTOR; 1.
DR Pfam; PF09294; Interfer-bind; 1.
DR Pfam; PF01108; Tissue_fac; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius}; Receptor {ECO:0000313|EMBL:EHB07603.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006813};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 271..289
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 41..139
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|Pfam:PF01108"
FT DOMAIN 157..256
FT /note="Interferon/interleukin receptor"
FT /evidence="ECO:0000259|Pfam:PF09294"
FT REGION 368..455
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 524..548
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 530..548
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 548 AA; 61306 MW; 1FA15A05FDB84D07 CRC64;
MMKPSKHSRG KRCERKERTY QLTKMLLSRQ TLAIRLLTLC FTVYVSLALD ASHDIPESAD
ENCDFKLAFR KYQLILSWEL KNRSIVPTHS TFQYTIMSKK ESMKTVENCT NITRSFCDLT
NVWQDMHETY IPMVEEFRGE TLLVQCLGSI TALNLSFEPP DFGIIGFADH INVVVQFPPV
APTIYGEDLH DQASLIIKEH SEDIDKRHEP KISGSFSGNF SYVINNLIPN TNYCISVYFE
PRSSRTITKP PLKCVLLQPA QESGSSKSVK IVIVIVIFVS VAISIILTLR QIGYVCLHTE
FPKVLIFHNF VVRIFPELPL SEEVNILEVI SINKKKKVWG YNYGDESDSE DEAPLRTIAG
GYTMHGLPGR LHSQVRTSPA SSQASHLGDP ADEESKEPER ETQPQPQPPA AQGPSPGQKE
GTSEPSERTE GLPQDPCPKV DDGNSSGGSG DKMTFNVDLN SVFLRVLHDD EEDSEEAALV
LPPPEEVVDL EEDPQEMESS LLVPGGEKLQ VLFPNLPPEC LWTGDDLSDK SDTSSSDVDD
IRDGYIMR
//
