ID G5BH55_HETGA Unreviewed; 379 AA.
AC G5BH55;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=WW domain-containing transcription regulator protein 1 {ECO:0000313|EMBL:EHB08616.1};
GN ORFNames=GW7_12912 {ECO:0000313|EMBL:EHB08616.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB08616.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB08616.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; JH170308; EHB08616.1; -; Genomic_DNA.
DR AlphaFoldDB; G5BH55; -.
DR STRING; 10181.G5BH55; -.
DR eggNOG; KOG0940; Eukaryota.
DR InParanoid; G5BH55; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR CDD; cd00201; WW; 1.
DR Gene3D; 2.20.70.10; -; 1.
DR Gene3D; 6.20.430.10; -; 1.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR17616:SF6; WW DOMAIN-CONTAINING TRANSCRIPTION REGULATOR PROTEIN 1; 1.
DR PANTHER; PTHR17616; YES-ASSOCIATED PROTEIN YAP1 FAMILY MEMBER; 1.
DR Pfam; PF00397; WW; 1.
DR SMART; SM00456; WW; 1.
DR SUPFAM; SSF51045; WW domain; 1.
DR PROSITE; PS01159; WW_DOMAIN_1; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000006813}.
FT DOMAIN 103..136
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT REGION 35..103
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 174..193
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 204..236
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 58..72
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 379 AA; 42314 MW; 8ECBCF214EB6A7D2 CRC64;
MNPSSAPPPL PPPGQQVIHV TQDLDTDLEA LFNSVMNPKP SSWRKKILPE SFFKEPDSGS
HSRQSSTDSS GGHPGPRLAG GPQHPRQQHA HLRQQSYDVT DELPLPPGWE MTFTATGQRY
FLNHIEKITT WQDPRKVMNQ PLNHLSLHPA ITSTPVPQRA MAVSQPNLVL NHQHQQQMAP
STLSPQNHPA QNPTSGLMSL PNALTTQQQQ QQKLRLQRIQ MERERIRMRQ EELMRQEAAL
CRQLPMEAES MATVQAAVNP PAMTPDMRSI TNNSSDPFLN GGPYHSREQS TDSGLGLGCY
SVPTTPEDFL SNVDEMDTGE NVGQTPMNIN HQQTRFPDFL DCLPGTNVDL GTLESEDLIP
LFNDVESALN KSEPFQTWL
//
