ID G5BJV7_HETGA Unreviewed; 415 AA.
AC G5BJV7;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Adipocyte plasma membrane-associated protein {ECO:0000256|ARBA:ARBA00015678};
GN Name=APMAP {ECO:0000313|EMBL:JAO03507.1};
GN ORFNames=GW7_03737 {ECO:0000313|EMBL:EHB09568.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB09568.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB09568.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
RN [2] {ECO:0000313|EMBL:JAO03507.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Kidney {ECO:0000313|EMBL:JAO03507.1};
RA Bens M., Sahm A., Jahn N., Morhart M., Holtze S., Hildebrandt T.B.,
RA Platzer M., Szafranski K.;
RT "FRAMA: From RNA-seq data to annotated mRNA assemblies.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the strictosidine synthase family.
CC {ECO:0000256|ARBA:ARBA00009191}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JH170668; EHB09568.1; -; Genomic_DNA.
DR EMBL; GEBF01000126; JAO03507.1; -; Transcribed_RNA.
DR RefSeq; XP_004874836.1; XM_004874779.2.
DR AlphaFoldDB; G5BJV7; -.
DR STRING; 10181.G5BJV7; -.
DR GeneID; 101719169; -.
DR KEGG; hgl:101719169; -.
DR CTD; 57136; -.
DR eggNOG; KOG1520; Eukaryota.
DR InParanoid; G5BJV7; -.
DR OMA; CCRTRAQ; -.
DR OrthoDB; 1066791at2759; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR Bgee; ENSHGLG00000001053; Expressed in adult mammalian kidney and 10 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016844; F:strictosidine synthase activity; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 1.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR018119; Strictosidine_synth_cons-reg.
DR PANTHER; PTHR10426:SF130; ADIPOCYTE PLASMA MEMBRANE-ASSOCIATED PROTEIN; 1.
DR PANTHER; PTHR10426; STRICTOSIDINE SYNTHASE-RELATED; 1.
DR Pfam; PF20067; SSL_N; 1.
DR Pfam; PF03088; Str_synth; 1.
DR SUPFAM; SSF63829; Calcium-dependent phosphotriesterase; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006813};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 37..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 200..287
FT /note="Strictosidine synthase conserved region"
FT /evidence="ECO:0000259|Pfam:PF03088"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 415 AA; 46435 MW; CAE7F33047730C16 CRC64;
MNEADGLRQR RPLRPQVLTD HGSAPEAKEG SSFSGRVFRM TFLVLAATLI LPLLGAMKLL
ESPIDPQPLS FKEPPLLLGV LQPNTKLRQA ERLFENQLTG PESIANIGDV MFTGTADGQV
LKLENGEAET IARFGSGPCK TREDEPACGR PLGIRVGPNG TLFVVDAYKG LFEVNPRKRE
VKLLLSSETP IEGRKMSFVN DLAITRDGRK IYFTDSSSKW QRRDYLFLVM EGTDDGRLLE
YDTETQEVRV LLDQLRFPNG VQLSPEEDFV LVVETTMARI RRVYVSGLMK GGADVFAENL
PGFPDNIRPS SSGGYWVAMS VIRQNPGFSM LDFLSDKPWI KTMIFKLLSQ ETVMKFLPRY
SLVLELSDSG AFRRSLHDPD GLVASYISEV HEHDGHLYLG SFRSPFLCRL NLQSV
//
