ID G5BQR9_HETGA Unreviewed; 2825 AA.
AC G5BQR9;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Matrix-remodeling-associated protein 5 {ECO:0000313|EMBL:EHB11630.1};
GN ORFNames=GW7_02004 {ECO:0000313|EMBL:EHB11630.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB11630.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB11630.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
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DR EMBL; JH171420; EHB11630.1; -; Genomic_DNA.
DR STRING; 10181.G5BQR9; -.
DR eggNOG; KOG0619; Eukaryota.
DR InParanoid; G5BQR9; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR CDD; cd00096; Ig; 5.
DR Gene3D; 2.60.40.10; Immunoglobulins; 12.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR45842:SF4; MATRIX-REMODELING-ASSOCIATED PROTEIN 5; 1.
DR PANTHER; PTHR45842; SYNAPTIC ADHESION-LIKE MOLECULE SALM; 1.
DR Pfam; PF07679; I-set; 4.
DR Pfam; PF13927; Ig_3; 8.
DR Pfam; PF13855; LRR_8; 1.
DR PRINTS; PR01832; VEGFRECEPTOR.
DR SMART; SM00409; IG; 12.
DR SMART; SM00408; IGc2; 12.
DR SMART; SM00369; LRR_TYP; 6.
DR SMART; SM00082; LRRCT; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 12.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS50835; IG_LIKE; 12.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000006813};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..2825
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003474584"
FT DOMAIN 483..567
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 584..676
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1844..1937
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1941..2032
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 2037..2129
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 2137..2230
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 2233..2332
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 2338..2424
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 2430..2524
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 2537..2622
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 2627..2720
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 2730..2825
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 286..318
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 679..728
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 845..1402
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1444..1517
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1529..1615
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1659..1712
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 293..310
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 681..695
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 928..946
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 959..973
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1025..1059
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1067..1089
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1090..1129
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1143..1159
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1161..1175
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1186..1220
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1236..1252
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1317..1343
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1563..1595
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1669..1694
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2825 AA; 309872 MW; 4C4DEE156058AAAC CRC64;
MRTRVPWAAL SVVLTLVCVH PRAARSCPHP CACYVPSEVH CTFRSLVAVP AGISEHVERM
NLGFNSIQAV SETSFAGLSK LELLMLHGND IPSIPDQALR DLSSLQVFKF SYNKLRVITR
QTFQGLSNLM RLHVDHNKIE FIHPQAFQGL LSLRLLHLEG NQLQQLHPGT FSTFTLLDHF
RLSTLRHLYL AENMMQRLPG GILQSMPLLE NLYLHGNPWA CDCEMKWFLD WTLRSKGILK
CKKDKAYAGG QWCTTCSSPR QLRKQEILKL PNVPCVKPSI ESPLKQNRSW VQEEEEEEEQ
DQEEEQPWDG QLALDDSSPA SRWNISLNMT DEHGNTVLLF CDIRKPTGLP SISLNQTEPP
EIDVNATVAL DFECPMTREN YEKLWKLIAY YSEVPVTLAQ EVLLGRDSGV SHQYHQDPNA
NPDALYYTGV RAQIEAWPTW VLQPSIHIQL NRRSSTAKKV ILSYSARYSQ TISAKDTVQA
RSPSWVMIEP SSGIHRAQTF LEGEDGQLSC HVKASESPSI SWVLPNGSVL RAPMQEQGSR
FSVLSGGWLK IRTVEQSDSG LYQCIAEVPD EVDQMAFRVL VQVPTVQPPE GSMVSIEKDA
GEPVMLPCSA SAVPEAHLSW ILPSKRIIDG SANASHAYMW ADGSLSIPSV QVSHAGYYRC
VAVNLHGADH VTVGLTVRRK GAGRSGKRGR RPGRPRADSR PRGDIVEDEG GSGVGGDESP
SGRTLHPKDQ EVFIKPEGEA TLGDKVPQKG RRKLKLWGPS EEKDLESNVA EGRRVFESRR
RINMANKQIN PERWADILAR VRGKNLPKAT EVPQDIVTTM LPSESPEGMS LSPVISLLAV
SPMQAVPDPE ESSAQGSLFG EEERVASTIS SPGMRQEHSH GGALLPKPQV TSPRLDDRVI
GEDLLETTED LSPAAVDLQW ELATSPGPEA YETSTPRTSE EPIGDQTATE AWSPPADVDR
IPKPRRNEEE PPLDEVSLAE SQRVKSVHPD GETYSQPDVV ETLEDHPLIP PTTAVRVEVS
SVPQSLEEHL EEQDVPAWSS VEEKPDSTRR VENRRTTQRT PSRKRVTKKK FLGETPTSRR
RESEEQDTGH TTLKAMSTAS PFAQPWATTR GTLPAGGVTT QANKTPSRMT TPPPALPTQP
SRRRPSGRRK LRPHKSRQRQ KPSPPAVSAS TDTSSPSPPS PLPATKTPKQ AQSSPVPTSW
VDNTAHVTKQ LDPQKPTESI SRGTTRRRNG KRPNRHRFST TATVSSKMPV SKPSPLETPH
EPAITSGSET RLPPLETGET DMVTRRKDYA TATPETPTAY HRVHVTTPVP FQPGAGREEL
TDHDFTHADS GGNDTRLRSE LLREGFSMPD PLVPTVGESK EASLPVALPG SPSWPLPRTA
LPGEPSTDTP GPGLREDPAD SXLEAVAATS QFAPSASLFA SVPQGKTGAP TTFSSAEVEL
SRSLAETTTA GWEPREGTVA HVPSETCSQK PIPTPGRVEE QATAFPPTAP ASLATTPLKP
TPITPGTPPT WAGPKENIFL NFVGNPETKA PVENIGGSQH RWRPEELSTP SHNQNGFNLS
PEQELAEERD NRRTNSLLHG PESHLPRERV HTARPLAGDP TKPTPPRGSL RPPLRATESP
LRYFGTFQPP HHFTSKLEIT AYPSRVFPDS KQFMIPQLPS MKPAAPTHPS KPSISSRLPD
QSTNRFNGYS KVFGNNNIPE PRIPVHQPAK PRLPYDSNGR FPFFTNRTFS FPQLGVTLKP
WTSTSPAPVT RERKVTPAPY NRFPSQSFLH VDLGPPAPPV LQPPRTMPPP SIYFQKVPLV
HTTQSSIFPM TSASQSPGSS HHSSLKIFVG GPPAPNFWTL GEKPQIITNP PQTLSVTAET
DALFPCEATG KPKPFITWTK VSTGALMTPN TRIQRFQVLK NGTLLIRRVQ VQDRGQYVCT
ASNLHGVDRM GVLLSVSVLQ PEILAPQFQD VTVYLGDTIA MECLAKGTPA PRISWIFPDR
RVWQTVSPAE GRVTLHQNRT LSIKDASFAD RGVYKCLASN AAGADSLAIR LHVAALPPVI
QQDKAENISL PPGLSIHIHC SAKAKPPASV RWVLRDGTQV RPSQFLHGNL FVFPNGTLHI
RNLAPRDSGR YECVATNLVG SARRAVRLSV QRTAAGARIT SASPRRTDVR YGGTLRLHCS
ASGDPWPRIL WRLPSKRMID ALFSFDSRAR AFSNGTLVVK SVTDKDAGEY LCVARNKVGD
DHAVLEVNVV MKPAKIERKE DSDHKVAYGG DLKVDCVATG LPNPEISWGL PDGSRLNSFM
QSDDGGGGRA KRYVLFNNGT LYFNEVGPRE EGDYTCFAQN QVGKDEMKVR VQVVARRTAV
RSRTPSVVQV SYGDRVTVAC EAPGEPVVTW LSPTSKAIPT NSEKYHIHPD GTLLIQKAQR
SDSGNYTCVV RGSAGEARKT VWVHVRVEPP TINGSPDAIT TVREVAPAGS RKFIHCKARG
VPTPRVLWAF PEGVILPAPY YGHRVTVHSN GSLDIRSLRK SDSVQLQCIA RSEGGEARMI
VQLTVLEPLE KPIFHGPESE KITATAGHTI SLNCSAAGSP PPTLLWVLPN GTELRAGQRL
HRFYHRGDGM MHITGLAPED AGAYRCVARN SAGHSERLVA LSVGLQPTLS KQYHNLVSII
NGESLQLHCS LPGAQQPGRF SWTLPNGVAL DSPQALGRFS VLDNGTLTVR EASVFDRGTY
TCRAQAEHGS SSSSSSSVLS IPVIVIAYPP RITSEPTPVI YTRPGSTVKL SCMAMGIPKA
EVSWELPDKS HLKAGAQARL YGNRFLHPQG SLTIQHATQR DAGFYKCKAQ NILGTDSKTT
YIHIY
//
