ID   G5BWT7_HETGA            Unreviewed;       268 AA.
AC   G5BWT7;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   RecName: Full=Mitochondrial fission regulator {ECO:0000256|RuleBase:RU369053};
GN   ORFNames=GW7_03078 {ECO:0000313|EMBL:EHB13743.1};
OS   Heterocephalus glaber (Naked mole rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC   Heterocephalus.
OX   NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB13743.1, ECO:0000313|Proteomes:UP000006813};
RN   [1] {ECO:0000313|EMBL:EHB13743.1, ECO:0000313|Proteomes:UP000006813}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21993625; DOI=10.1038/nature10533;
RA   Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA   Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA   Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA   Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA   Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA   Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT   "Genome sequencing reveals insights into physiology and longevity of the
RT   naked mole rat.";
RL   Nature 479:223-227(2011).
CC   -!- FUNCTION: May play a role in mitochondrial aerobic respiration. May
CC       also regulate mitochondrial organization and fission.
CC       {ECO:0000256|ARBA:ARBA00037378}.
CC   -!- FUNCTION: Plays a role in mitochondrial aerobic respiration. Regulates
CC       mitochondrial organization and fission.
CC       {ECO:0000256|RuleBase:RU369053}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000256|ARBA:ARBA00004173,
CC       ECO:0000256|RuleBase:RU369053}.
CC   -!- SIMILARITY: Belongs to the MTFR1 family.
CC       {ECO:0000256|ARBA:ARBA00005807, ECO:0000256|RuleBase:RU369053}.
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DR   EMBL; JH172227; EHB13743.1; -; Genomic_DNA.
DR   AlphaFoldDB; G5BWT7; -.
DR   STRING; 10181.G5BWT7; -.
DR   Ensembl; ENSHGLT00000071781; ENSHGLP00000034401; ENSHGLG00000046609.
DR   Ensembl; ENSHGLT00100092235; ENSHGLP00100042229; ENSHGLG00100045198.
DR   InParanoid; G5BWT7; -.
DR   Proteomes; UP000006813; Unassembled WGS sequence.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0009060; P:aerobic respiration; IEA:UniProtKB-UniRule.
DR   GO; GO:0000266; P:mitochondrial fission; IEA:UniProtKB-UniRule.
DR   InterPro; IPR007972; Mtfr1.
DR   PANTHER; PTHR14215:SF1; MITOCHONDRIAL FISSION REGULATOR 1; 1.
DR   PANTHER; PTHR14215; PROTEIN OF UNKNOWN FUNCTION DUF729; 1.
DR   Pfam; PF05308; Mito_fiss_reg; 1.
PE   3: Inferred from homology;
KW   Mitochondrion {ECO:0000256|RuleBase:RU369053};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006813}.
SQ   SEQUENCE   268 AA;  29053 MW;  B56F62D81CA90108 CRC64;
     MGTLGKATQL SQSIVRKIGT NLFLIQCPRV QFQLTSHATD WNSSHPGEDA VVSFADVAWV
     ATEGGEGSTR LRTEVRSNLP LQDDLFFEKP PSRHISLPNL SQEEPPPKTT ALANEAALQK
     ICALENELAA LRAQIAKIVT LQEQQNLTAG DLDSTISVII APPPPPPPQP LPVGLHQSAS
     ATDLIKEVKR SEQDVKTKPV DATDPDGLIA EAVKNKSAYR YRSNSQSEVE KGVPKSELET
     TSETAFFGPH MLKSTRKMKA VIENVSSS
//