ID G5BZA8_HETGA Unreviewed; 347 AA.
AC G5BZA8;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE SubName: Full=SH2 domain-containing adapter protein D {ECO:0000313|EMBL:EHB14619.1};
GN ORFNames=GW7_06764 {ECO:0000313|EMBL:EHB14619.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB14619.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB14619.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
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DR EMBL; JH172536; EHB14619.1; -; Genomic_DNA.
DR AlphaFoldDB; G5BZA8; -.
DR STRING; 10181.G5BZA8; -.
DR eggNOG; ENOG502QUXW; Eukaryota.
DR InParanoid; G5BZA8; -.
DR OMA; SELPCKA; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR PANTHER; PTHR15127; HEAVYWEIGHT, ISOFORM A; 1.
DR PANTHER; PTHR15127:SF33; SH2 DOMAIN-CONTAINING ADAPTER PROTEIN D; 1.
DR Pfam; PF00017; SH2; 1.
DR PRINTS; PR00401; SH2DOMAIN.
DR SMART; SM00252; SH2; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR PROSITE; PS50001; SH2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006813};
KW SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191}.
FT DOMAIN 243..338
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT REGION 1..77
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 90..132
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 144..188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 206..234
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..57
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 171..188
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 210..227
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 347 AA; 39042 MW; D4ECDE916D171ECB CRC64;
MAKWLRDSLS LGGRRPPPQP PTPDYSESDI LLAYRTQKNL DFEDPYEDAD SRPEPDPAAP
PDSKSPGDSK YDSPRHRLIK VEAVDMARAK ALLGSPGDGD ELEVDTEYSD PFDAQPQPPP
SDDGYVEPYD AQWTISELPC KAVQLYDTPY EEQDQEPEEN GTPSEQRLQQ SRLPLEDERP
ADEYDQPWEW KKDHISRAFA VQFDSPEWER TSGSAKELRR RPPRSPQPAE RVDPALPLEK
QPWFHGPLSR ADAENLLSLC KEGSYLVRLS ETSPQDCSLS LRSSQGFLHL KFTRTRANQV
VLGQHSGPFA SVPELVLHYS ARPLPVQGAE HLVLLYPVVT QSPCPAP
//
