ID G5CTL0_MNELE Unreviewed; 299 AA.
AC G5CTL0;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=TGF-beta ligand {ECO:0000313|EMBL:AEP16387.1};
GN Name=Tgf4 {ECO:0000313|EMBL:AEP16387.1};
OS Mnemiopsis leidyi (Sea walnut) (Warty comb jellyfish).
OC Eukaryota; Metazoa; Ctenophora; Tentaculata; Lobata; Bolinopsidae;
OC Mnemiopsis.
OX NCBI_TaxID=27923 {ECO:0000313|EMBL:AEP16387.1};
RN [1] {ECO:0000313|EMBL:AEP16387.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=21931657; DOI=10.1371/journal.pone.0024152;
RA Pang K., Ryan J.F., Baxevanis A.D., Martindale M.Q.;
RT "Evolution of the TGF-beta Signaling Pathway and Its Potential Role in the
RT Ctenophore, Mnemiopsis leidyi.";
RL PLoS ONE 6:E24152-E24152(2011).
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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DR EMBL; JN380185; AEP16387.1; -; mRNA.
DR AlphaFoldDB; G5CTL0; -.
DR HOGENOM; CLU_1497991_0_0_1; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR CDD; cd19379; TGF_beta_GSDF; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR015615; TGF-beta-rel.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR PANTHER; PTHR11848:SF296; TGF-BETA FAMILY PROFILE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 2: Evidence at transcript level;
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354}; Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 182..299
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
SQ SEQUENCE 299 AA; 34085 MW; 1D350E55F5AFBCED CRC64;
MECQRNVYKW IYESSQGGPP VSQRLAPCQE DRTDCLVLHS DHQKGLVRVR EVELHVYLPN
VALGETGDTV SILVQRKLPR GIREDRFVVT WSESWVHLNI SQSIEDSDFW LRDGICVSAM
IDGVSSVPEP WRFSENNTDD QAFVMVWSEE DMSVPQNMKT KRSHRARDRF RETAIIHSPF
ERSTKSSKFG GEKCKLEPLY INFRDLGWES WVIAPPGLEV GSCSGYCMRE DISSNYNLLI
NNISRDPELY RLYGLAGIRT ERTCVPTSFL PTVLMFIGKD QDIVVQLVDD ILVGGCGCV
//
