ID G5DEJ8_9CAUD Unreviewed; 264 AA.
AC G5DEJ8;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 08-NOV-2023, entry version 38.
DE RecName: Full=site-specific DNA-methyltransferase (adenine-specific) {ECO:0000256|ARBA:ARBA00011900};
DE EC=2.1.1.72 {ECO:0000256|ARBA:ARBA00011900};
GN ORFNames=SPN3US_0105 {ECO:0000313|EMBL:AEP83938.1};
OS Salmonella phage SPN3US.
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC Seoulvirus; Seoulvirus SPN3US.
OX NCBI_TaxID=1090134 {ECO:0000313|EMBL:AEP83938.1, ECO:0000313|Proteomes:UP000008314};
RN [1] {ECO:0000313|EMBL:AEP83938.1, ECO:0000313|Proteomes:UP000008314}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22106383; DOI=10.1128/JVI.06344-11;
RA Lee J.H., Shin H., Kim H., Ryu S.;
RT "Complete Genome Sequence of Salmonella Bacteriophage SPN3US.";
RL J. Virol. 85:13470-13471(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an
CC N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-
CC homocysteine; Xref=Rhea:RHEA:15197, Rhea:RHEA-COMP:12418, Rhea:RHEA-
CC COMP:12419, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:90615, ChEBI:CHEBI:90616; EC=2.1.1.72;
CC Evidence={ECO:0000256|ARBA:ARBA00001279};
CC -!- SIMILARITY: Belongs to the N(4)/N(6)-methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00006594}.
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DR EMBL; JN641803; AEP83938.1; -; Genomic_DNA.
DR RefSeq; YP_009153399.1; NC_027402.1.
DR REBASE; 40983; M.Sph3ORF105P.
DR GeneID; 24667577; -.
DR KEGG; vg:24667577; -.
DR OrthoDB; 8399at10239; -.
DR Proteomes; UP000008314; Genome.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0009007; F:site-specific DNA-methyltransferase (adenine-specific) activity; IEA:UniProtKB-EC.
DR Gene3D; 1.10.1020.10; Adenine-specific Methyltransferase, Domain 2; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR023095; Ade_MeTrfase_dom_2.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR012263; M_m6A_EcoRV.
DR InterPro; IPR012327; MeTrfase_D12.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR00571; dam; 1.
DR PANTHER; PTHR30481; DNA ADENINE METHYLASE; 1.
DR PANTHER; PTHR30481:SF3; DNA ADENINE METHYLASE; 1.
DR Pfam; PF02086; MethyltransfD12; 1.
DR PIRSF; PIRSF000398; M_m6A_EcoRV; 1.
DR PRINTS; PR00505; D12N6MTFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:AEP83938.1};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
SQ SEQUENCE 264 AA; 29686 MW; EEDE47BABEA38CE7 CRC64;
MGGKSRVLPE LLQVLPDAEY FVEPFVGAGS VFLNTKYPNY ILGDTNPDLI ELLTMARDRP
EALILEAKAL FANGTDRGLY MERREGFNSE ATTGKPNLQR AAMFLYLTRH GYNGLCRYNQ
SGGFNVPYGQ HPNGVYFPEE EILAWAKRCS ETNVELLCAD FRDILNKCPS NAVIYADPPY
IPLSDTAKHA QYHSKEFSQA DHRELAKLLK QQAADGNKVV LSNADTLLTR DIYYGFTWRE
VQVGRYMSAD ANKRKAVTEL IGTL
//
