ID G5E8Q7_MOUSE Unreviewed; 427 AA.
AC G5E8Q7;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=SAC3 domain containing 1 {ECO:0000313|Ensembl:ENSMUSP00000109161.2};
GN Name=Sac3d1 {ECO:0000313|Ensembl:ENSMUSP00000109161.2,
GN ECO:0000313|MGI:MGI:1913656};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000109161.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000109161.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000109161.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000109161.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000109161.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; NP_598439.3; NM_133678.3.
DR AlphaFoldDB; G5E8Q7; -.
DR SMR; G5E8Q7; -.
DR EPD; G5E8Q7; -.
DR MaxQB; G5E8Q7; -.
DR ProteomicsDB; 338776; -.
DR Antibodypedia; 52625; 16 antibodies from 8 providers.
DR Ensembl; ENSMUST00000113533.3; ENSMUSP00000109161.2; ENSMUSG00000024790.9.
DR GeneID; 66406; -.
DR KEGG; mmu:66406; -.
DR UCSC; uc008ghl.1; mouse.
DR AGR; MGI:1913656; -.
DR CTD; 29901; -.
DR MGI; MGI:1913656; Sac3d1.
DR VEuPathDB; HostDB:ENSMUSG00000024790; -.
DR GeneTree; ENSGT00940000160988; -.
DR HOGENOM; CLU_047746_1_0_1; -.
DR OMA; IFTHAYN; -.
DR OrthoDB; 3665923at2759; -.
DR PhylomeDB; G5E8Q7; -.
DR TreeFam; TF350231; -.
DR BioGRID-ORCS; 66406; 2 hits in 80 CRISPR screens.
DR Proteomes; UP000000589; Chromosome 19.
DR Bgee; ENSMUSG00000024790; Expressed in cleaving embryo and 240 other cell types or tissues.
DR Gene3D; 1.25.40.990; -; 1.
DR InterPro; IPR000717; PCI_dom.
DR InterPro; IPR045107; SAC3/GANP/THP3.
DR InterPro; IPR005062; SAC3/GANP/THP3_conserved.
DR PANTHER; PTHR12436; 80 KDA MCM3-ASSOCIATED PROTEIN; 1.
DR PANTHER; PTHR12436:SF38; SAC3 DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF03399; SAC3_GANP; 1.
DR PROSITE; PS50250; PCI; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:G5E8Q7,
KW ECO:0007829|MaxQB:G5E8Q7};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT DOMAIN 229..397
FT /note="PCI"
FT /evidence="ECO:0000259|PROSITE:PS50250"
FT REGION 1..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 101..142
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 427 AA; 46412 MW; 986769315D093561 CRC64;
MGRFKGENRS QARWIMGGVS KGRGSGKSRK PRQAAFGQTG ARVCPSSPRQ DAVPRFRWPG
DAECASSTHT PTMSGCKLPM GLCPDMCPAA ERARRERERR LHRLEVEPGG RGNAPRADPK
RTVKEYSRPA AGKPRPPPSL LRPPPVLLAT VRYLAGEVAG RGDVSCAEVA SFVADRLRAV
RLDLSLQGVD DADAATVLEA ALATLLAVVA RVRPEETRGA ADPVLLQTQV QEGFGSLRRC
YARGKGPYPR QAAFQGLFLL YNLGSVEALQ EVLQLPAALR ACPPLQAALA VDAAFREDNH
ARLFRLLRTL PYLQSCAVQE HIGYARRKAL ARLSRALSTP KGQTLPLDFI EHFLALDGLQ
EARDLCQAHG LTLDKDRVVF LRGQYSEEGL PPPGAYHILV GNKLQGHTLE DVVMAEEGDI
HRPGSAA
//
