ID G5EC30_CAEEL Unreviewed; 582 AA.
AC G5EC30;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 100.
DE SubName: Full=Anion transporter SULP-7d {ECO:0000313|EMBL:AAX34428.1};
DE SubName: Full=STAS domain-containing protein {ECO:0000313|EMBL:CAA92028.2};
GN Name=sulp-7 {ECO:0000313|EMBL:CAA92028.2,
GN ECO:0000313|WormBase:W04G3.6d};
GN ORFNames=CELE_W04G3.6 {ECO:0000313|EMBL:CAA92028.2}, W04G3.6
GN {ECO:0000313|WormBase:W04G3.6d};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CAA92028.2, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CAA92028.2, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CAA92028.2,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
RN [2] {ECO:0000313|EMBL:CAA92028.2}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CAA92028.2};
RA Sulson J.E., Waterston R.;
RL Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:AAX34428.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=15814591; DOI=10.1152/ajpcell.00071.2005;
RA Sherman T., Chernova M.N., Clark J.S., Jiang L., Alper S.L., Nehrke K.;
RT "The abts and sulp families of anion transporters from Caenorhabditis
RT elegans.";
RL Am. J. Physiol. 289:C341-C351(2005).
RN [4] {ECO:0000313|EMBL:CAA92028.2}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CAA92028.2};
RG WormBase Consortium;
RA WormBase;
RL Submitted (AUG-2023) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU362052}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362052}.
CC -!- SIMILARITY: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
CC {ECO:0000256|RuleBase:RU362052}.
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DR EMBL; AY887916; AAX34428.1; -; mRNA.
DR EMBL; BX284606; CAA92028.2; -; Genomic_DNA.
DR PIR; T26165; T26165.
DR RefSeq; NP_001033571.1; NM_001038482.3.
DR SMR; G5EC30; -.
DR STRING; 6239.W04G3.6d.1; -.
DR PaxDb; 6239-W04G3-6d; -.
DR EnsemblMetazoa; W04G3.6d.1; W04G3.6d.1; WBGene00012259.
DR GeneID; 189195; -.
DR KEGG; cel:CELE_W04G3.6; -.
DR AGR; WB:WBGene00012259; -.
DR WormBase; W04G3.6d; CE37418; WBGene00012259; sulp-7.
DR eggNOG; KOG0236; Eukaryota.
DR HOGENOM; CLU_003182_9_2_1; -.
DR OMA; FSHRDEW; -.
DR OrthoDB; 1067648at2759; -.
DR Reactome; R-CEL-427601; Multifunctional anion exchangers.
DR Proteomes; UP000001940; Chromosome X.
DR Bgee; WBGene00012259; Expressed in larva and 2 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015106; F:bicarbonate transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0015108; F:chloride transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0019531; F:oxalate transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0008271; F:secondary active sulfate transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015116; F:sulfate transmembrane transporter activity; IBA:GO_Central.
DR CDD; cd07042; STAS_SulP_like_sulfate_transporter; 1.
DR Gene3D; 3.30.750.24; STAS domain; 1.
DR InterPro; IPR018045; S04_transporter_CS.
DR InterPro; IPR011547; SLC26A/SulP_dom.
DR InterPro; IPR001902; SLC26A/SulP_fam.
DR InterPro; IPR002645; STAS_dom.
DR InterPro; IPR036513; STAS_dom_sf.
DR NCBIfam; TIGR00815; sulP; 1.
DR PANTHER; PTHR11814:SF257; ANION TRANSPORTER SULP-7D; 1.
DR PANTHER; PTHR11814; SULFATE TRANSPORTER; 1.
DR Pfam; PF01740; STAS; 1.
DR Pfam; PF00916; Sulfate_transp; 1.
DR SUPFAM; SSF52091; SpoIIaa-like; 1.
DR PROSITE; PS01130; SLC26A; 1.
DR PROSITE; PS50801; STAS; 1.
PE 1: Evidence at protein level;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362052};
KW Proteomics identification {ECO:0007829|PeptideAtlas:G5EC30};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362052};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362052}; Transport {ECO:0000256|RuleBase:RU362052}.
FT TRANSMEM 80..99
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 119..141
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 153..172
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 184..201
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 207..226
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 238..257
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 283..303
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 323..342
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 362..380
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 387..407
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 419..446
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT DOMAIN 471..570
FT /note="STAS"
FT /evidence="ECO:0000259|PROSITE:PS50801"
SQ SEQUENCE 582 AA; 64025 MW; 1E8E3CB9B09B764D CRC64;
MKKKQNQSWK NYIPITKWLP NYSISENLIN DIIGGVTVGI LNVPQGMAYA SLVGLKPVYG
LYTSLFPSLI YMFFGTSRHV ALGVFAVVSL MSGSCNLRVT QEIISNNGTN MTSTEVEAIS
INVVKSLGLA VGLIQIIMGL FKANYLISYL SDQIILGFTT GAAVHVLTAQ LNKILGVALP
RHSGIGKLFF IYQDLITAII GEKVNVITFG ASVVAIVILY ISKYILTPRF CAKTLVPIPF
DLFLIVIGTI IADWFQVEER WGVKVVGDIP TGFPNPALPD LFMFRHVIGD ALAIAIVSVV
VTVSMGKVIA KKHNYEIDVR QEFFALGIVA STCSMFPCWP ATTALARTLI NDNAGTKTQI
SAIFSALVLT LVLFFIGQYL EGLPMCLLSC IVIVALRGMF LHLQNFVTLW RVSKYDWAIF
AITFFATVCL DVVPGLFIGT IFALLLSILR IQRSSPTLLD DDCAESGKTF VVFFASSLFY
FNCERFDRKI QKIVAQITGE KDISKAAVST EDMAMIDSHK PQKTVIFDMN GVSSIDLSGA
NLLVKIQKDL ITNDISFKIR NPSDHIFSFL TGLPNTDQLF ES
//
