ID G5ELZ2_TOBAC Unreviewed; 573 AA.
AC G5ELZ2;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=peptidylprolyl isomerase {ECO:0000256|PROSITE-ProRule:PRU00277};
DE EC=5.2.1.8 {ECO:0000256|PROSITE-ProRule:PRU00277};
GN Name=FKBP62 {ECO:0000313|EMBL:BAL14273.1};
GN Synonyms=LOC107824095 {ECO:0000313|RefSeq:XP_016506305.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|EMBL:BAL14273.1};
RN [1] {ECO:0000313|EMBL:BAL14273.1}
RP NUCLEOTIDE SEQUENCE.
RA Ishikawa M., Iki T., Yoshikawa M., Meshi T.;
RT "Cyclophilin 40 Facilitates HSP90-mediated RISC Assembly in Plants.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [3] {ECO:0000313|RefSeq:XP_016506305.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[protein]-peptidylproline (omega=180) = [protein]-
CC peptidylproline (omega=0); Xref=Rhea:RHEA:16237, Rhea:RHEA-
CC COMP:10747, Rhea:RHEA-COMP:10748, ChEBI:CHEBI:83833,
CC ChEBI:CHEBI:83834; EC=5.2.1.8; Evidence={ECO:0000256|PROSITE-
CC ProRule:PRU00277};
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DR EMBL; AB671736; BAL14273.1; -; mRNA.
DR RefSeq; NP_001313055.1; NM_001326126.1.
DR RefSeq; XP_016506305.1; XM_016650819.1.
DR STRING; 4097.G5ELZ2; -.
DR PaxDb; 4097-G5ELZ2; -.
DR GeneID; 107824095; -.
DR KEGG; nta:107824095; -.
DR OMA; TVCQKKT; -.
DR OrthoDB; 25281at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IBA:GO_Central.
DR GO; GO:0061077; P:chaperone-mediated protein folding; IBA:GO_Central.
DR Gene3D; 3.10.50.40; -; 3.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR046357; PPIase_dom_sf.
DR InterPro; IPR001179; PPIase_FKBP_dom.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR001440; TPR_1.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR46512; PEPTIDYLPROLYL ISOMERASE; 1.
DR PANTHER; PTHR46512:SF9; TETRATRICOPEPTIDE REPEAT DOMAIN 9; 1.
DR Pfam; PF00254; FKBP_C; 3.
DR Pfam; PF00515; TPR_1; 1.
DR SMART; SM00028; TPR; 3.
DR SUPFAM; SSF54534; FKBP-like; 3.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50059; FKBP_PPIASE; 3.
DR PROSITE; PS50005; TPR; 1.
PE 2: Evidence at transcript level;
KW Isomerase {ECO:0000256|PROSITE-ProRule:PRU00277,
KW ECO:0000313|RefSeq:XP_016506305.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Rotamase {ECO:0000256|PROSITE-ProRule:PRU00277};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT DOMAIN 55..143
FT /note="PPIase FKBP-type"
FT /evidence="ECO:0000259|PROSITE:PS50059"
FT DOMAIN 171..260
FT /note="PPIase FKBP-type"
FT /evidence="ECO:0000259|PROSITE:PS50059"
FT DOMAIN 288..383
FT /note="PPIase FKBP-type"
FT /evidence="ECO:0000259|PROSITE:PS50059"
FT REPEAT 483..516
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 553..573
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 573 AA; 63731 MW; 4B8166D810E8FF49 CRC64;
MEEDFDIPPA EGMDEDMDLP DDPIMKVGEE KEIGNQGLKK KLVKEGEGWE TPEAGDEVEV
HYTGTLLDGT KFDSSRDRGD PFKFTLGQGQ VIKGWDQGIK TMKKGENAIF TIPPELAYGE
SGSPPTIPPN ATLQFDVELL SWVSVKDICK DGGIFKKILA EGEKWENPKD FDEVLVKYEA
LLENGTVVGK SDGVEFTVQD GYFCPALAKA VKTMKKGEKV QLTVKPQYGF GEKGKPASSD
GGAVPSNATL QINLELVSWK IVSSVTDDKK VVKKILKEGE GYEKPNEGAV VKLKLIGKLQ
DGTVFIKKGH DGENEDELFE FKTDEEQVID GLDRAVMTMK KGEVALLTIA PEYAFGSSES
KQDLAVIPPN STVHYEVELV SFVKDKESWD MNTPEKIEAA GKKKEEGNAL FKAGKYTRAS
KRYEKAAKFI EYDTSFSEEE KKQSKALKIS CNLNNAACKL KLKDYKQAEK LCTKVLELES
TNVKALYRRA QAYMNMADLD LAEFDIKKAL EIDPNNRDVK LEYKALKDKV KEFNKKDAKF
YGNMFAKLNK LETANSSKSA PKEPEPMSID SKA
//
