ID G5GCI9_9BACT Unreviewed; 406 AA.
AC G5GCI9;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE RecName: Full=CobW C-terminal domain-containing protein {ECO:0000259|SMART:SM00833};
GN ORFNames=HMPREF9332_01266 {ECO:0000313|EMBL:EHG22768.1};
OS Alloprevotella rava F0323.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Alloprevotella.
OX NCBI_TaxID=679199 {ECO:0000313|EMBL:EHG22768.1, ECO:0000313|Proteomes:UP000015993};
RN [1] {ECO:0000313|EMBL:EHG22768.1, ECO:0000313|Proteomes:UP000015993}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0323 {ECO:0000313|EMBL:EHG22768.1,
RC ECO:0000313|Proteomes:UP000015993};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Izard J., Blanton J.M.,
RA Baranova O.V., Tanner A.C., Dewhirst F.E., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E.,
RA Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Prevotella sp. oral taxon 302 str. F0323.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHG22768.1}.
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DR EMBL; ACZK01000022; EHG22768.1; -; Genomic_DNA.
DR RefSeq; WP_009347739.1; NZ_JH376830.1.
DR AlphaFoldDB; G5GCI9; -.
DR STRING; 679199.HMPREF9332_01266; -.
DR PATRIC; fig|679199.3.peg.1391; -.
DR eggNOG; COG0523; Bacteria.
DR HOGENOM; CLU_017452_2_0_10; -.
DR OrthoDB; 9808822at2; -.
DR Proteomes; UP000015993; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR43603; COBW DOMAIN-CONTAINING PROTEIN DDB_G0274527; 1.
DR PANTHER; PTHR43603:SF1; COBW DOMAIN-CONTAINING PROTEIN DDB_G0274527; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SMART; SM00833; CobW_C; 1.
DR SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000015993}.
FT DOMAIN 287..403
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|SMART:SM00833"
FT REGION 241..282
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 241..260
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 406 AA; 46486 MW; 573B4A54E4C6F06F CRC64;
MIEQTPVLLL TGYLGSGKTT LVNRILTNSS GIKFAVIVND IGEVNIDANL IEKGGIVGKK
DDSLVALQNG CICCTLKTDL VEQVHDITSL KKFDYIVIEA SGVCEPAPIA QTLCSIPTMY
PGMAKDGIAR LDCIATVVDA LRLRDEFNSG EDLQRKDIGE EDIANLVIQQ VEFCNMILLN
KASEVKPEEL AKIKEILRAL QPKAEIIECD YGNVALDKLL NTQLFNFKTE ASSATWLAEL
EKPQEEHHEE EEEHEHHHHE HEHHHDHCHH HHHHHDHEGG ETEEYGIGTY VYYRRQPFEL
SLFDDFVARH WPKGIIRTKG LCWFRDERNT CYVFEQAGKQ IGLSSIGQWY ATMPEDELRD
MMAREPGLRR DWDEKYGDRM QKIVFIGQHL DREEIDRLLD KCLVKE
//
