ID   G5GI87_9FIRM            Unreviewed;       257 AA.
AC   G5GI87;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   24-JAN-2024, entry version 35.
DE   RecName: Full=DUF218 domain-containing protein {ECO:0000259|Pfam:PF02698};
GN   ORFNames=HMPREF9333_01277 {ECO:0000313|EMBL:EHI55562.1};
OS   Johnsonella ignava ATCC 51276.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Johnsonella.
OX   NCBI_TaxID=679200 {ECO:0000313|EMBL:EHI55562.1, ECO:0000313|Proteomes:UP000003011};
RN   [1] {ECO:0000313|EMBL:EHI55562.1, ECO:0000313|Proteomes:UP000003011}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51276 {ECO:0000313|EMBL:EHI55562.1,
RC   ECO:0000313|Proteomes:UP000003011};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Izard J., Blanton J.M.,
RA   Baranova O.V., Dewhirst F.E., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA   Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E.,
RA   Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA   Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA   Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA   Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Johnsonella ignava ATCC 51276.";
RL   Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EHI55562.1}.
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DR   EMBL; ACZL01000021; EHI55562.1; -; Genomic_DNA.
DR   RefSeq; WP_005540801.1; NZ_JH378832.1.
DR   AlphaFoldDB; G5GI87; -.
DR   STRING; 679200.HMPREF9333_01277; -.
DR   PATRIC; fig|679200.3.peg.1360; -.
DR   eggNOG; COG2949; Bacteria.
DR   HOGENOM; CLU_051474_0_1_9; -.
DR   OrthoDB; 9782395at2; -.
DR   Proteomes; UP000003011; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd06259; YdcF-like; 1.
DR   InterPro; IPR003848; DUF218.
DR   PANTHER; PTHR30336; INNER MEMBRANE PROTEIN, PROBABLE PERMEASE; 1.
DR   PANTHER; PTHR30336:SF6; INTEGRAL MEMBRANE PROTEIN-RELATED; 1.
DR   Pfam; PF02698; DUF218; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003011};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        40..63
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          83..221
FT                   /note="DUF218"
FT                   /evidence="ECO:0000259|Pfam:PF02698"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..15
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   257 AA;  28686 MW;  E98D77215A584649 CRC64;
     MLFKNKSVQT QADTAKQKHT SHKKQNLKTA PKLVRAIINL FKLAAAASVL LVLFIALCNF
     IVISSTKKYI LDTKDISKIS KADCVLVLGC YVHPGGHMSA MLKDRMDEAI SVYGTGAAQN
     MIVSGDHGKA DYDEVNIMKN YAIENDIPSQ CIFMDHAGFS TYESMYRADY IFGAKKMIIV
     TQEYHLYRAV YDARAMGIEA YGVAADRHIY PDQTLRNNIR ETAARVKDVI YCIFKPKPSY
     LGDKIPLSGD GNITNDH
//