ID G5GKJ2_9FIRM Unreviewed; 622 AA.
AC G5GKJ2;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|PROSITE:PS50878};
GN ORFNames=HMPREF9333_02084 {ECO:0000313|EMBL:EHI54721.1};
OS Johnsonella ignava ATCC 51276.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Johnsonella.
OX NCBI_TaxID=679200 {ECO:0000313|EMBL:EHI54721.1, ECO:0000313|Proteomes:UP000003011};
RN [1] {ECO:0000313|EMBL:EHI54721.1, ECO:0000313|Proteomes:UP000003011}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51276 {ECO:0000313|EMBL:EHI54721.1,
RC ECO:0000313|Proteomes:UP000003011};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Izard J., Blanton J.M.,
RA Baranova O.V., Dewhirst F.E., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E.,
RA Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Johnsonella ignava ATCC 51276.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHI54721.1}.
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DR EMBL; ACZL01000043; EHI54721.1; -; Genomic_DNA.
DR AlphaFoldDB; G5GKJ2; -.
DR STRING; 679200.HMPREF9333_02084; -.
DR PATRIC; fig|679200.3.peg.2194; -.
DR eggNOG; COG1403; Bacteria.
DR eggNOG; COG3344; Bacteria.
DR HOGENOM; CLU_013584_14_3_9; -.
DR Proteomes; UP000003011; Unassembled WGS sequence.
DR GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd00085; HNHc; 1.
DR CDD; cd01651; RT_G2_intron; 1.
DR Gene3D; 1.10.30.50; -; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR030931; Group_II_RT_mat.
DR InterPro; IPR002711; HNH.
DR InterPro; IPR003615; HNH_nuc.
DR InterPro; IPR000477; RT_dom.
DR NCBIfam; TIGR04416; group_II_RT_mat; 1.
DR PANTHER; PTHR34047:SF2; NUCLEAR INTRON MATURASE 1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR34047; NUCLEAR INTRON MATURASE 1, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF01844; HNH; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SMART; SM00507; HNHc; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000003011}.
FT DOMAIN 90..356
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
SQ SEQUENCE 622 AA; 71850 MW; 10DB400B0DA0E457 CRC64;
MVTVSTSKQT LKQSKIRYTE YYDLQKVLDD LYEDSGNNKV FSNLMELITS RENIKLAYRS
IKGNKGSHTA GVDGRTIKHL SRLNEEEYIS LIQKQFHWYK PRPVKRVEIL KPNGKIRPLG
IPTIIDRIVQ QCILQILEPI CEAKFHDSSY GFRPNRSTEH AIAECARLMQ IQHLHYVVDI
DIQGFFDNVY HAKLIRQLWN LGIQDKKLLC IIKEMLKADI VMPDKKVITP TKGTPQGGIL
SPLLSNIVLN ELDWWVSSQW LTMPTHYPYK QRTNSQGTEI KSHTYRALRT SNLKEIYIVR
YADDFKIFCR NYYDAERTYQ AVTKWLQDRL KLNVSEEKSK ITNLKQRYSE FLGFKLKVKP
KGKKFVVQSH INDKALKKAK ENISKCVADI KRPANEKEQY KAIAKYNATV SGLHNYYQIA
TNVSLDFAKI AFHIKKQMNN RLDIKTGGTL NKGFIKEKYG KSKQLRFLNG HPLIPVGYIR
TKDAKHKKKV VNKYTVKGRA FIHKNLQIDV DTLVWLMKHP VLDKSIEFAD NRISLFAAQY
GRCGVTGIKL TPNDIHCHHK IPLEQGGTDS YSNLILVTEA VHILIHATKE DAIQKYIKEL
GLTLKQIEKC NKLRKMAGLP PI
//
