ID G5IN86_9CLOT Unreviewed; 842 AA.
AC G5IN86;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Glycoside hydrolase family 38 central domain-containing protein {ECO:0000259|SMART:SM00872};
GN ORFNames=HMPREF9473_04964 {ECO:0000313|EMBL:EHI57057.1};
OS Hungatella hathewayi WAL-18680.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Hungatella.
OX NCBI_TaxID=742737 {ECO:0000313|EMBL:EHI57057.1, ECO:0000313|Proteomes:UP000005384};
RN [1] {ECO:0000313|EMBL:EHI57057.1, ECO:0000313|Proteomes:UP000005384}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WAL-18680 {ECO:0000313|EMBL:EHI57057.1,
RC ECO:0000313|Proteomes:UP000005384};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Finegold S.M., Summanen P.H.,
RA Molitoris D.R., Song M., Daigneault M., Allen-Vercoe E., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Clostridium hathewayi WAL-18680.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC {ECO:0000256|ARBA:ARBA00009792}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHI57057.1}.
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DR EMBL; ADLN01000127; EHI57057.1; -; Genomic_DNA.
DR RefSeq; WP_006782952.1; NZ_JH379030.1.
DR AlphaFoldDB; G5IN86; -.
DR PATRIC; fig|742737.3.peg.4949; -.
DR HOGENOM; CLU_003442_2_1_9; -.
DR OrthoDB; 9764050at2; -.
DR Proteomes; UP000005384; Unassembled WGS sequence.
DR GO; GO:0004559; F:alpha-mannosidase activity; IEA:InterPro.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR CDD; cd10814; GH38N_AMII_SpGH38_like; 1.
DR Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR InterPro; IPR015341; Glyco_hydro_38_cen.
DR InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR InterPro; IPR000602; Glyco_hydro_38_N.
DR InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR PANTHER; PTHR46017; ALPHA-MANNOSIDASE 2C1; 1.
DR PANTHER; PTHR46017:SF2; MANNOSYLGLYCERATE HYDROLASE; 1.
DR Pfam; PF09261; Alpha-mann_mid; 1.
DR Pfam; PF01074; Glyco_hydro_38N; 1.
DR SMART; SM00872; Alpha-mann_mid; 1.
DR SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000005384}.
FT DOMAIN 274..349
FT /note="Glycoside hydrolase family 38 central"
FT /evidence="ECO:0000259|SMART:SM00872"
SQ SEQUENCE 842 AA; 97976 MW; A89D0A250F7B41AF CRC64;
MNSEKRIISV LHHTHWDREW YQTFEAMQIR LRDVIRHIVT MIENHQIEYF YLDGQTCVLD
DYREIVSKEE FSRLEELIRR GKIQVGPWYV LADEFLCPPE ACVKNLEIGM KTAKEYGSFC
RLGYLPDTFG HIGSMPQILK EFGIDCAVVW RGTNPSDCEV WWEGNDKSRL ATLVLSTRDG
YYQTFLKHQD YERELDAYLD FHNRKRSWNC PVLMDGADHT VCNDDVLKKL RAYENDRNVQ
FQEVLANQLC ERLLKCDIQE TVKGELRDAS KIYVLSGTWS SRMYLKVMNQ KCVDAMVHRV
EFLNAWEAGK SRSEALLEHM WKKLLVNQAH DSICGCSIDE VHSDMESRFR QILESANQYA
DTVLEQLYPY EYMDSSVFNE WLHMIHNTPY QERTLVTAVI LVRKKEDQGG IALYDGDQKL
DIRIAERVEK EVFFHHSFAE PWYEDAVEYR IEVHITFQGM EHRCFQIKTC PPEAECPPET
VDFISNEYYE LRVEEGSVSV RQKLTGKQYK NQHIWTSVPD AGDSYNSSWL EGQETVLGKI
ETVQCRKDCM KQTMVIRWRL EAPAGLDVKR TGPCEERKEL TITTRFQLIP GSPLIRVHSQ
VHNEAKNHKL KIEFRMPEIE YHESDTAFDL VRREVRKPSA GAARPNEELE ICQDPSNSQI
YAGDIQIVHI GMQEYEVEKR GEGDVCSLTA LRCTGDLSRR DLRTRGGGAG PGYETPGGQC
IGDWEFDYGL IYGRELFSPE HVIELKTSPI IKQSYVWSPD ERRLWLTGNI LYSSYQYSDG
GWVLRMFHQK DWEEVINVRL GRTGKVWLSD LGGLKKEFLG EGDSFSIRVP GCKIITMRVE
EL
//
