ID G5LSS5_SALET Unreviewed; 501 AA.
AC G5LSS5;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=Cell invasion protein SipB {ECO:0000313|EMBL:EHC34085.1};
GN ORFNames=LTSEALA_4107 {ECO:0000313|EMBL:EHC34085.1};
OS Salmonella enterica subsp. enterica serovar Alachua str. R6-377.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=913241 {ECO:0000313|EMBL:EHC34085.1, ECO:0000313|Proteomes:UP000004642};
RN [1] {ECO:0000313|EMBL:EHC34085.1, ECO:0000313|Proteomes:UP000004642}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R6-377 {ECO:0000313|EMBL:EHC34085.1,
RC ECO:0000313|Proteomes:UP000004642};
RX PubMed=21859443; DOI=10.1186/1471-2164-12-425;
RA den Bakker H.C., Moreno Switt A.I., Govoni G., Cummings C.A., Ranieri M.L.,
RA Degoricija L., Hoelzer K., Rodriguez-Rivera L.D., Brown S., Bolchacova E.,
RA Furtado M.R., Wiedmann M.;
RT "Genome sequencing reveals diversification of virulence factor content and
RT possible host adaptation in distinct subpopulations of Salmonella
RT enterica.";
RL BMC Genomics 12:425-425(2011).
CC -!- SUBCELLULAR LOCATION: Host membrane {ECO:0000256|ARBA:ARBA00004301};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004301}. Secreted
CC {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the SctE/SipB/YopB family.
CC {ECO:0000256|ARBA:ARBA00035640}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHC34085.1}.
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DR EMBL; AFCJ01001788; EHC34085.1; -; Genomic_DNA.
DR AlphaFoldDB; G5LSS5; -.
DR PATRIC; fig|913241.3.peg.3104; -.
DR Proteomes; UP000004642; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.120.330; Nucleotidyltransferases domain 2; 2.
DR InterPro; IPR006972; BipB-like_C.
DR InterPro; IPR032391; IpaB/BipB/SctE_N.
DR InterPro; IPR003895; T3SS_SctE/BipB.
DR Pfam; PF04888; SseC; 1.
DR Pfam; PF16535; T3SSipB; 1.
DR PRINTS; PR01375; BACINVASINB.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Host membrane {ECO:0000256|ARBA:ARBA00022870};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Virulence {ECO:0000256|ARBA:ARBA00023026}.
FT TRANSMEM 228..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..337
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..142
FT /note="IpaB/BipB/SctE N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16535"
FT DOMAIN 167..498
FT /note="Translocator protein BipB-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF04888"
FT COILED 89..116
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 501 AA; 52800 MW; D36F1AB28300F781 CRC64;
MTLLGDVSLS QLESRLAVWQ AMIESQKEMG IQVSKEFQTA LGEAQEATDL YEASIKKTDT
AKSVYDAAAK KLTQAQNKLQ SLDPADPGYA QAEAAVEQAG KEATEAKEAL DKATDATVKA
GTDAKAKAEK ADNILTKFQG TANAASQNQV SQGEQDNLSN VARLTMLMAM FIEIVGKNTE
ESLQNDLALF NALQEGRQAE MEKKSAEFQE ETRKAEETNR IMGCIGKVLG ALLTIVSVVA
AVFTGGASLA LAAVGLAVMV ADEIVKAATG VSFIQQALNP IMEHVLKPLM ELIGKAITKA
LEGLGVDKKT AEMAGSIVGA IVAAIAMVAV IVVVAVVGKG AAAKLGNALS KMMGETIKKL
VPNVLKQLAQ NGSKLFTQGM QRITSGLGNV GSKMGLQTNA LSKELVGNTL NKVALGMEVT
NTAAQSAGGV AEGVFIKNAS EALADFMLAR FAMDQIQQWL KQSVEIFGEN QKVTAELQKA
MSSAVQQNAD ASRFILRQSR A
//
