ID G5QPI0_SALRU Unreviewed; 503 AA.
AC G5QPI0;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN ORFNames=LTSERUB_4934 {ECO:0000313|EMBL:EHC81955.1};
OS Salmonella enterica subsp. enterica serovar Rubislaw str. A4-653.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=913081 {ECO:0000313|EMBL:EHC81955.1, ECO:0000313|Proteomes:UP000004903};
RN [1] {ECO:0000313|EMBL:EHC81955.1, ECO:0000313|Proteomes:UP000004903}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A4-653 {ECO:0000313|EMBL:EHC81955.1,
RC ECO:0000313|Proteomes:UP000004903};
RX PubMed=21859443; DOI=10.1186/1471-2164-12-425;
RA den Bakker H.C., Moreno Switt A.I., Govoni G., Cummings C.A., Ranieri M.L.,
RA Degoricija L., Hoelzer K., Rodriguez-Rivera L.D., Brown S., Bolchacova E.,
RA Furtado M.R., Wiedmann M.;
RT "Genome sequencing reveals diversification of virulence factor content and
RT possible host adaptation in distinct subpopulations of Salmonella
RT enterica.";
RL BMC Genomics 12:425-425(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHC81955.1}.
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DR EMBL; AFCT01001798; EHC81955.1; -; Genomic_DNA.
DR AlphaFoldDB; G5QPI0; -.
DR PATRIC; fig|913081.3.peg.3813; -.
DR Proteomes; UP000004903; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF30; F-BOX DNA HELICASE 1; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:EHC81955.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 181..231
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|Pfam:PF00580"
FT DOMAIN 357..459
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13361"
FT REGION 471..503
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 503 AA; 57139 MW; B8ECF233CBA0018C CRC64;
MSYPDTPEQA AIIAWKGTRL VVSACAGSGK TTTLRRFAEE NPTERMLYVA YNRAIRDEAE
QKFPFNVICK TSHQLAWPTV GKHYSKRLVN TLRLTDVARA LNSRNWLLAR LTLDVLNRFM
CSASANISEE LLPDQDDCKG LQPERILFSA QNIWAMMSSR QETFPVTHDT YLKIYQLSKP
DLSARYTTVL FDEAQDANPV TSAIILEQPC RVVLVGDTHQ QIYRFRGADN ALCAPQLECA
DRLWLTHSFR FGPEIAEVAN RLLSLKGDTH KITGKGGSDR VLTIVPRTFG HHAILHRSVC
GVIRTALHWS LAGKKVFWVG GMESYKIEDL LDLYWFSIDM TERMRHDRLT REYRDYDEYL
QIAEDTGDVE MKQAIFILEQ FFPLPDRLTT LREQRVTTES DADVTVCTAH RGKGLEWDRV
QLYDDFADIL DPEMPESKRH DEINLMYVAT TRARKILILD PVLSELLAQP PAEDISGSSH
EVSGGTEVST ESGDKGAEYV PES
//
