ID G5QZR4_SALSE Unreviewed; 319 AA.
AC G5QZR4;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE RecName: Full=Zinc transport protein ZntB {ECO:0000256|HAMAP-Rule:MF_01565};
GN Name=zntB {ECO:0000256|HAMAP-Rule:MF_01565};
GN ORFNames=LTSESEN_2436 {ECO:0000313|EMBL:EHC89178.1};
OS Salmonella enterica subsp. enterica serovar Senftenberg str. A4-543.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=913082 {ECO:0000313|EMBL:EHC89178.1, ECO:0000313|Proteomes:UP000005065};
RN [1] {ECO:0000313|EMBL:EHC89178.1, ECO:0000313|Proteomes:UP000005065}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A4-543 {ECO:0000313|EMBL:EHC89178.1,
RC ECO:0000313|Proteomes:UP000005065};
RX PubMed=21859443; DOI=10.1186/1471-2164-12-425;
RA den Bakker H.C., Moreno Switt A.I., Govoni G., Cummings C.A., Ranieri M.L.,
RA Degoricija L., Hoelzer K., Rodriguez-Rivera L.D., Brown S., Bolchacova E.,
RA Furtado M.R., Wiedmann M.;
RT "Genome sequencing reveals diversification of virulence factor content and
RT possible host adaptation in distinct subpopulations of Salmonella
RT enterica.";
RL BMC Genomics 12:425-425(2011).
CC -!- FUNCTION: Zinc transporter. Acts as a Zn(2+):proton symporter, which
CC likely mediates zinc ion uptake. {ECO:0000256|HAMAP-Rule:MF_01565}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H(+)(out) + Zn(2+)(out) = H(+)(in) + Zn(2+)(in);
CC Xref=Rhea:RHEA:71195, ChEBI:CHEBI:15378, ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|HAMAP-Rule:MF_01565};
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000256|HAMAP-
CC Rule:MF_01565}; Multi-pass membrane protein {ECO:0000256|HAMAP-
CC Rule:MF_01565}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass
CC membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35)
CC family. {ECO:0000256|ARBA:ARBA00009765, ECO:0000256|HAMAP-
CC Rule:MF_01565}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHC89178.1}.
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DR EMBL; AFCU01000788; EHC89178.1; -; Genomic_DNA.
DR AlphaFoldDB; G5QZR4; -.
DR PATRIC; fig|913082.3.peg.1891; -.
DR Proteomes; UP000005065; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005385; F:zinc ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR CDD; cd12833; ZntB-like_1; 1.
DR Gene3D; 3.30.460.20; CorA soluble domain-like; 1.
DR Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 2.
DR HAMAP; MF_01565; ZntB; 1.
DR InterPro; IPR045861; CorA_cytoplasmic_dom.
DR InterPro; IPR045863; CorA_TM1_TM2.
DR InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR InterPro; IPR023714; Zn_transp_ZntB.
DR PANTHER; PTHR46494; CORA FAMILY METAL ION TRANSPORTER (EUROFUNG); 1.
DR PANTHER; PTHR46494:SF3; ZINC TRANSPORT PROTEIN ZNTB; 1.
DR Pfam; PF01544; CorA; 1.
DR SUPFAM; SSF143865; CorA soluble domain-like; 1.
DR SUPFAM; SSF144083; Magnesium transport protein CorA, transmembrane region; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519, ECO:0000256|HAMAP-
KW Rule:MF_01565};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475, ECO:0000256|HAMAP-
KW Rule:MF_01565}; Ion transport {ECO:0000256|HAMAP-Rule:MF_01565};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_01565};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP-
KW Rule:MF_01565};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|HAMAP-
KW Rule:MF_01565}; Transport {ECO:0000256|HAMAP-Rule:MF_01565};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|HAMAP-Rule:MF_01565}.
FT TRANSMEM 260..281
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01565"
FT TRANSMEM 293..313
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01565"
SQ SEQUENCE 319 AA; 35959 MW; 0C5C4E81B66B934B CRC64;
MNVPDAVFAW LLDGRGGVKP LEDNDVIDSQ HPCWLHLNYT HPDSARWLAS TPLLPNNVRD
ALAGESSRPR VSRMGEGTLI TLRCINGSTD ERPDQLVAMR LYMDERFIVS TRQRKVLALD
DVVSDLQEGT GPVDCGGWLV DVCDALTDHA SEFIEELHDK IIDLEDNLLD QQIPPRGFLA
LLRKQLIVMR RYMAPQRDVY ARLASERLPW MSDDHRRRMQ DIADRLGRGL DEIDACIART
GIMADEIAQV MQESLARRTY TMSLMAMVFL PSTFLTGLFG VNLGGIPGGG WRFGFSLFCI
LLVVLIGGVT LWLHRSKWL
//
