ID   G5SNA2_9BACT            Unreviewed;       615 AA.
AC   G5SNA2;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   24-JAN-2024, entry version 32.
DE   SubName: Full=2-oxoacid:acceptor oxidoreductase, alpha subunit {ECO:0000313|EMBL:EHH01168.1};
GN   ORFNames=HMPREF9441_00831 {ECO:0000313|EMBL:EHH01168.1};
OS   Paraprevotella clara YIT 11840.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC   Paraprevotella.
OX   NCBI_TaxID=762968 {ECO:0000313|EMBL:EHH01168.1, ECO:0000313|Proteomes:UP000003598};
RN   [1] {ECO:0000313|EMBL:EHH01168.1, ECO:0000313|Proteomes:UP000003598}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YIT 11840 {ECO:0000313|EMBL:EHH01168.1,
RC   ECO:0000313|Proteomes:UP000003598};
RA   Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA   Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA   Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA   Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA   Chinwalla A., Mardis E.R., Wilson R.K.;
RL   Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EHH01168.1}.
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DR   EMBL; AFFY01000015; EHH01168.1; -; Genomic_DNA.
DR   RefSeq; WP_008618136.1; NZ_JH376591.1.
DR   AlphaFoldDB; G5SNA2; -.
DR   STRING; 762968.HMPREF9441_00831; -.
DR   GeneID; 78582026; -.
DR   PATRIC; fig|762968.3.peg.742; -.
DR   eggNOG; COG0674; Bacteria.
DR   eggNOG; COG1014; Bacteria.
DR   HOGENOM; CLU_017038_1_0_10; -.
DR   OrthoDB; 9794954at2; -.
DR   Proteomes; UP000003598; Unassembled WGS sequence.
DR   GO; GO:0016903; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors; IEA:InterPro.
DR   CDD; cd07034; TPP_PYR_PFOR_IOR-alpha_like; 1.
DR   Gene3D; 3.40.50.920; -; 1.
DR   Gene3D; 3.40.50.970; -; 1.
DR   Gene3D; 3.40.920.10; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR   InterPro; IPR022367; 2-oxoacid/accept_OxRdtase_asu.
DR   InterPro; IPR033412; PFOR_II.
DR   InterPro; IPR019752; Pyrv/ketoisovalerate_OxRed_cat.
DR   InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR   InterPro; IPR002869; Pyrv_flavodox_OxRed_cen.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   NCBIfam; TIGR03710; OAFO_sf; 1.
DR   PANTHER; PTHR32154:SF20; 2-OXOGLUTARATE OXIDOREDUCTASE SUBUNIT KORA; 1.
DR   PANTHER; PTHR32154; PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR   Pfam; PF17147; PFOR_II; 1.
DR   Pfam; PF01558; POR; 1.
DR   Pfam; PF01855; POR_N; 1.
DR   SUPFAM; SSF53323; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR   SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          22..211
FT                   /note="Pyruvate/ketoisovalerate oxidoreductase catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF01558"
FT   DOMAIN          258..446
FT                   /note="Pyruvate flavodoxin/ferredoxin oxidoreductase
FT                   pyrimidine binding"
FT                   /evidence="ECO:0000259|Pfam:PF01855"
FT   DOMAIN          513..578
FT                   /note="Pyruvate:ferredoxin oxidoreductase core"
FT                   /evidence="ECO:0000259|Pfam:PF17147"
SQ   SEQUENCE   615 AA;  66310 MW;  EEEE79F143B339BE CRC64;
     MADRLEVKEL DQVVVRFSGD SGDGMQLAGN IFSTVSATVG NDICTFPDYP ADIRAPQGSL
     TGVSGFQVHI GAQRVYTPGD KCDVLVAMNA AALKTQYRYA KSTACIIIDT DCFQAKDLQK
     AAFTTDNPIE ELGIKNDVIA APITQMVKAC LADSGMENKA ILKCRNMFAL GLVCWLFNRD
     LEIAFNMLRE KFAKKPAVAE ANIKVIQAGY DYGANTHASV AHTYKVESKT KKPGKYMDIM
     GNKATAYGFI AAAEKAGKRL FLGSYPITPA TDVLHELSKH KSLGVTTVQC EDEIAGCASS
     IGASFAGALA VTSTSGPGVC LKSEAMNLAV ITELPLVILN VQRGGPSTGL PTKSEQTDLL
     QALFGRNGES PMPVIAATSP TNCFDAAYYA SKMALEHMTP VVLLTDAFVA NGSGAFKLPD
     LNDYPDICPP YVTPEMAGSY TPYMRNPDTQ VRYWAIPGQE GYMHILGGLE KDGRTGAIST
     DPENHDKMCR LRAEKVARIP VPDVEVQGCV DDAELLIVGF GGTYGHLHSA MDEMVATGKK
     VALAHFSYLN PLPANTAEVL KRYKKVVVAE QNLGQFAAYL RMKVDGFVPY QFNQVKGQPF
     VVSELVAAFT EIYNK
//