ID   G5ZYB9_9PROT            Unreviewed;       355 AA.
AC   G5ZYB9;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=Adenylate/guanylate cyclase family protein {ECO:0000313|EMBL:EHI48891.1};
GN   ORFNames=HIMB100_00010240 {ECO:0000313|EMBL:EHI48891.1};
OS   SAR116 cluster alpha proteobacterium HIMB100.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; SAR116 cluster.
OX   NCBI_TaxID=909943 {ECO:0000313|EMBL:EHI48891.1, ECO:0000313|Proteomes:UP000004261};
RN   [1] {ECO:0000313|EMBL:EHI48891.1, ECO:0000313|Proteomes:UP000004261}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=strain HIMB100 {ECO:0000313|Proteomes:UP000004261};
RX   PubMed=22675578; DOI=10.4056/sigs.1854551;
RA   Grote J., Bayindirli C., Bergauer K., Carpintero de Moraes P., Chen H.,
RA   D'Ambrosio L., Edwards B., Fernandez-Gomez B., Hamisi M., Logares R.,
RA   Nguyen D., Rii Y.M., Saeck E., Schutte C., Widner B., Church M.J.,
RA   Steward G.F., Karl D.M., Delong E.F., Eppley J.M., Schuster S.C.,
RA   Kyrpides N.C., Rappe M.S.;
RT   "Draft genome sequence of strain HIMB100, a cultured representative of the
RT   SAR116 clade of marine Alphaproteobacteria.";
RL   Stand. Genomic Sci. 5:269-278(2011).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EHI48891.1}.
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DR   EMBL; AFXB01000008; EHI48891.1; -; Genomic_DNA.
DR   AlphaFoldDB; G5ZYB9; -.
DR   STRING; 909943.HIMB100_00010240; -.
DR   eggNOG; COG2114; Bacteria.
DR   OrthoDB; 315417at2; -.
DR   Proteomes; UP000004261; Unassembled WGS sequence.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   Gene3D; 6.10.250.780; -; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   PANTHER; PTHR45655; GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2; 1.
DR   PANTHER; PTHR45655:SF13; SOLUBLE GUANYLATE CYCLASE GCY-35-RELATED; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000004261}.
FT   DOMAIN          161..286
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   355 AA;  39154 MW;  F27208D3960DD82D CRC64;
     MCAMLKTDFV STFALPVFSL DSVLNFSEIN ASFFEIFGDV QGKPITSLSD EFNERKCVRK
     ISAGQAYRFK IFTSDVRKTP YSVELRQTAS GYIGFAVEAA DAAKAEAMLA SYSEMMEKQN
     RILKAEKNKS EKLLQSLLPA TFIDELQSLS GTTPKTMKKA GLLMVALPQV QHLLGGLEAD
     DMFAELDELF TCFDLLAEIH ACQRLEATPN SYLAALPLLS PDSPACETLA QFALDAIEVI
     KLRQSQIHIL CKFGLHLGEV TTGIVGKTHL SFMAMGTGVA AVADITGQAD DLQVCCSDTI
     YQYSEPLRHA LQLNSNGPDM SDKDPVYRLS PEFGTRNQDK LQQCISRAKT LRRNF
//