ID G6C3Y9_9FUSO Unreviewed; 302 AA.
AC G6C3Y9;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=UTP--glucose-1-phosphate uridylyltransferase {ECO:0000256|ARBA:ARBA00012415, ECO:0000256|RuleBase:RU361259};
DE EC=2.7.7.9 {ECO:0000256|ARBA:ARBA00012415, ECO:0000256|RuleBase:RU361259};
DE AltName: Full=UDP-glucose pyrophosphorylase {ECO:0000256|RuleBase:RU361259};
GN ORFNames=HMPREF9093_01282 {ECO:0000313|EMBL:EHI78505.1};
OS Fusobacterium sp. oral taxon 370 str. F0437.
OC Bacteria; Fusobacteriota; Fusobacteriia; Fusobacteriales; Fusobacteriaceae;
OC Fusobacterium.
OX NCBI_TaxID=861452 {ECO:0000313|EMBL:EHI78505.1, ECO:0000313|Proteomes:UP000003908};
RN [1] {ECO:0000313|EMBL:EHI78505.1, ECO:0000313|Proteomes:UP000003908}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0437 {ECO:0000313|EMBL:EHI78505.1,
RC ECO:0000313|Proteomes:UP000003908};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA Chinwalla A., Mardis E.R., Wilson R.K.;
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha-D-glucose 1-phosphate + H(+) + UTP = diphosphate + UDP-
CC alpha-D-glucose; Xref=Rhea:RHEA:19889, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:33019, ChEBI:CHEBI:46398, ChEBI:CHEBI:58601,
CC ChEBI:CHEBI:58885; EC=2.7.7.9;
CC Evidence={ECO:0000256|ARBA:ARBA00000872,
CC ECO:0000256|RuleBase:RU361259};
CC -!- SIMILARITY: Belongs to the UDPGP type 2 family.
CC {ECO:0000256|ARBA:ARBA00006890, ECO:0000256|RuleBase:RU361259}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHI78505.1}.
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DR EMBL; AGAD01000141; EHI78505.1; -; Genomic_DNA.
DR AlphaFoldDB; G6C3Y9; -.
DR STRING; 861452.HMPREF9093_01282; -.
DR PATRIC; fig|861452.3.peg.1176; -.
DR eggNOG; COG1210; Bacteria.
DR HOGENOM; CLU_029499_1_2_0; -.
DR Proteomes; UP000003908; Unassembled WGS sequence.
DR GO; GO:0003983; F:UTP:glucose-1-phosphate uridylyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR GO; GO:0006011; P:UDP-glucose metabolic process; IEA:InterPro.
DR CDD; cd02541; UGPase_prokaryotic; 1.
DR InterPro; IPR005771; GalU_uridylyltTrfase_bac/arc.
DR InterPro; IPR005835; NTP_transferase_dom.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR NCBIfam; TIGR01099; galU; 1.
DR PANTHER; PTHR43197; UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR PANTHER; PTHR43197:SF1; UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR Pfam; PF00483; NTP_transferase; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Nucleotidyltransferase {ECO:0000256|RuleBase:RU361259};
KW Transferase {ECO:0000256|RuleBase:RU361259}.
FT DOMAIN 13..275
FT /note="Nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF00483"
SQ SEQUENCE 302 AA; 33892 MW; 1A97B0E57533319F CRC64;
MSLKEAFMKK VTKAVIPAAG LGTRVLPATK ALPKEMLTIV DKPSLQYIVE ELVASGITDI
VIITGRNKNS IEDHFDFSYE LENTLKNEHK ADLLDKVSHI STMANIYYVR QNMPLGLGHA
ILKAKSFIGD EPFVIALGDD IIYNPEKPVT KQMIEKYELY GKSLIGCQEV EVEDVTKYGI
AKLGNKFDEA TFQMLDFLEK PSIEDAPSKM ACLGRYLLSG KVFKYLEETK PGKNGEIQLT
DGILAMMKDG EDVLSYKFIG KRYDIGSKAG LLKANIEFGL RNEETKNDIK EYLKNLDINK
IY
//
