ID G6EBK3_9SPHN Unreviewed; 790 AA.
AC G6EBK3;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 24-JAN-2024, entry version 57.
DE SubName: Full=ATP-dependent Clp protease ATP-binding subunit ClpA {ECO:0000313|EMBL:EHJ61285.1};
GN Name=clpA {ECO:0000313|EMBL:EHJ61285.1};
GN ORFNames=NSU_1724 {ECO:0000313|EMBL:EHJ61285.1};
OS Novosphingobium pentaromativorans US6-1.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Novosphingobium.
OX NCBI_TaxID=1088721 {ECO:0000313|EMBL:EHJ61285.1, ECO:0000313|Proteomes:UP000004030};
RN [1] {ECO:0000313|EMBL:EHJ61285.1, ECO:0000313|Proteomes:UP000004030}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=US6-1 {ECO:0000313|EMBL:EHJ61285.1,
RC ECO:0000313|Proteomes:UP000004030};
RX PubMed=22275104; DOI=10.1128/JB.06476-11;
RA Luo Y.R., Kang S.G., Kim S.J., Kim M.R., Li N., Lee J.H., Kwon K.K.;
RT "Genome sequence of benzo(a)pyrene-degrading bacterium Novosphingobium
RT pentaromativorans US6-1.";
RL J. Bacteriol. 194:907-907(2012).
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|ARBA:ARBA00008675, ECO:0000256|RuleBase:RU004432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHJ61285.1}.
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DR EMBL; AGFM01000024; EHJ61285.1; -; Genomic_DNA.
DR RefSeq; WP_007012639.1; NZ_CP009291.1.
DR AlphaFoldDB; G6EBK3; -.
DR STRING; 1088721.JI59_11460; -.
DR KEGG; npn:JI59_11460; -.
DR PATRIC; fig|1088721.3.peg.1703; -.
DR eggNOG; COG0542; Bacteria.
DR OrthoDB; 9803641at2; -.
DR Proteomes; UP000004030; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0043335; P:protein unfolding; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR013461; ClpA.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR02639; ClpA; 1.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF111; ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPA; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 1.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|RuleBase:RU004432};
KW Hydrolase {ECO:0000313|EMBL:EHJ61285.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432}; Protease {ECO:0000313|EMBL:EHJ61285.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000004030};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}.
FT DOMAIN 1..146
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
FT REGION 144..176
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 754..790
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 145..176
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 790 AA; 87139 MW; B35655D5655C98AD CRC64;
MPSFAQSLEK TLHSALSHAS ERSHEYATLE HLLLALIDDP DAAQVMQACG VDLGDLGDVV
RQYLDQEYQS LKTEEKGDPA PTAGFQRVIQ RAILHVQSSG KDTVTGANVL VALFSERDSY
AVYFLQQQDM SRLDAVSYIS HGIGKGGKRI EDRSPKGSEE QTPTPEEKAE TKAANKKDSA
LDQFCVNLNE KALAGKVDPL IGRGPEVDRT IQILCRRSKN NPLYVGDPGV GKTAIAEGLA
RKIVEGEVPE VLSEAVIYSL DMGSLLAGTR YRGDFEERLK QVVAELEKMP HAILFIDEIH
TVIGAGATSG GAMDASNLLK PALSGGTIRC IGSTTYKEFR NHFEKDRALL RRFQKIDVNE
PTVEDTVKIL KGLRTAFEDH HGVRYTPDAI KTAVELSARY INDRKLPDKA IDVIDEVGAM
QMLVPPSRRK KTITAREIEQ VIATMARIPP KSVSSDDKKA LENLERDLKR VVFGQDKAIE
VLSTAMKLSR AGLRDPDKPI GSFLFSGPTG VGKTEVAKQL ATIMGIPMQR FDMSEYMERH
SVSRLIGAPP GYVGFDQGGL LTDAIDQQPH CVLLLDEIEK AHPDLFNILL QVMDNGKLTD
HHGKTVDFRN VVLIMTTNAG ASDMAKQGIG FGDTSKADAG EEAVKQMFSP EFRNRLDAIV
PFAYLAKETI SRVVDKFILQ LELQLADQNV HIQFDSDARE WLGHRGYDRL YGARPMARVI
QERVKQPLAE ELLFGKLAHG GEVHVSVKED ALNFELTPAP PKETKSRKKK APAKKPVRKT
GPQPEENTDD
//
