ID G6F0X7_9PROT Unreviewed; 873 AA.
AC G6F0X7;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 24-JAN-2024, entry version 57.
DE RecName: Full=DNA mismatch repair protein MutS {ECO:0000256|ARBA:ARBA00021982};
GN ORFNames=CIN_11300 {ECO:0000313|EMBL:EHD13771.1};
OS Commensalibacter intestini A911.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Acetobacteraceae.
OX NCBI_TaxID=1088868 {ECO:0000313|EMBL:EHD13771.1, ECO:0000313|Proteomes:UP000005939};
RN [1] {ECO:0000313|EMBL:EHD13771.1, ECO:0000313|Proteomes:UP000005939}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A911 {ECO:0000313|EMBL:EHD13771.1,
RC ECO:0000313|Proteomes:UP000005939};
RA Lee W.-J., Kim E.-K.;
RT "Genome Sequence of Commensalibacter intestini A911, isolated from
RT Drosophila gut.";
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: This protein is involved in the repair of mismatches in DNA.
CC It is possible that it carries out the mismatch recognition step. This
CC protein has a weak ATPase activity. {ECO:0000256|ARBA:ARBA00024647}.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271, ECO:0000256|RuleBase:RU003756}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHD13771.1}.
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DR EMBL; AGFR01000007; EHD13771.1; -; Genomic_DNA.
DR RefSeq; WP_008854120.1; NZ_AGFR01000007.1.
DR AlphaFoldDB; G6F0X7; -.
DR STRING; 1088868.CIN_11300; -.
DR PATRIC; fig|1088868.3.peg.1134; -.
DR eggNOG; COG0249; Bacteria.
DR OrthoDB; 9802448at2; -.
DR Proteomes; UP000005939; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 6.10.140.430; -; 1.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR005748; DNA_mismatch_repair_MutS.
DR InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR01070; mutS1; 1.
DR PANTHER; PTHR11361:SF34; DNA MISMATCH REPAIR PROTEIN MSH1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF01624; MutS_I; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 2.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF55271; DNA repair protein MutS, domain I; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|RuleBase:RU003756};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204, ECO:0000256|RuleBase:RU003756};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU003756};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003756}.
FT DOMAIN 701..717
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
SQ SEQUENCE 873 AA; 97132 MW; 49208446ACE0FAD6 CRC64;
MTIPSSTGAT PVMAQWFSLK DQFPDALLFF RMGDFFELFF NDAEAAANAL DIALTARGNH
GGQPIPMCGV PVGTASNYLA RLIKKGFKVA VAEQTESPAN RPKGQKGPLS RDVVRLITPG
TLTEDELLQA GQENYVLSIV FSAKHKTTKL GVAWIDISTG FFETSSINSS KLNDLLGRIN
PSEIICSKDI QLNDYENRRT ILRDTHTLKT AEKELSSLFN VNTFDALGNF NDEEIIAGYE
LVHYIQKTQA GKLPQLSRPQ SQQYETILAI DPATRNSLDI LQNSDGDQKF TLFSSVSYTV
TAPGARMLAN WLAAPLTQIK YIQTRQEGWI YLQQDALLLT TLRKTLKGAP DIARALSRLS
LGRGQPRDLA SIRNGLEIGR NIAEVLKQFE KETGRSCSLI QNTSEYLLYG EELLLSLRAA
LEENPPLKLE EGFIIKAGYN DELDAYRRLR DNSRQVIASL QEDYKNKYNI STLKIKHHTQ
LGHIIEVSNT AGNKIQNHPD LILRQGTANL SRFTTIELNE LSGKILEANT LAAEKEKQLF
TELIHKTLQE STLPLLAKSI AIIDVLQSCA TLYSKHHWCI PTLTDDTSFE LINCRHPVVE
AALQHKTTFT PNSCNLSKNN KIMLLTGPNM AGKSTFLRQV ALSVILAQAG LPVPASEAKI
GIVDHLFSRV GASDDLAHGR STFMVEMTES ASILNQAGPR SLVVIDEIGR GTSTLDGMAI
AWSMLETLHN TIQCRTIFAT HFHELVQSTQ HLKSCKPFTM KVQEWKGSII FQYEVIPGAA
EHSWGIHVAQ LAGVPLPTLK RAQQLLQNLE TQYNDPQITL PLSSPFIEQT PTNQSLPYQY
EEITEILKMI DPDELTPKKS LNILYKLKKL IDK
//
