ID G6FUK3_9CYAN Unreviewed; 689 AA.
AC G6FUK3;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Sodium/hydrogen exchanger {ECO:0000313|EMBL:EHC12933.1};
GN ORFNames=FJSC11DRAFT_2550 {ECO:0000313|EMBL:EHC12933.1};
OS Fischerella thermalis JSC-11.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Hapalosiphonaceae;
OC Fischerella.
OX NCBI_TaxID=741277 {ECO:0000313|EMBL:EHC12933.1, ECO:0000313|Proteomes:UP000004344};
RN [1] {ECO:0000313|EMBL:EHC12933.1, ECO:0000313|Proteomes:UP000004344}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JSC-11 {ECO:0000313|EMBL:EHC12933.1,
RC ECO:0000313|Proteomes:UP000004344};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Land M.L., Hauser L., Sarkisova S., Bryant D.A., Brown I.,
RA Woyke T.J.;
RT "The draft genome of Fischerella sp. JSC-11.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHC12933.1}.
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DR EMBL; AGIZ01000007; EHC12933.1; -; Genomic_DNA.
DR RefSeq; WP_009457229.1; NZ_AGIZ01000007.1.
DR AlphaFoldDB; G6FUK3; -.
DR GeneID; 60766627; -.
DR PATRIC; fig|741277.3.peg.2099; -.
DR Proteomes; UP000004344; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR CDD; cd01988; Na_H_Antiporter_C; 1.
DR CDD; cd00293; USP_Like; 1.
DR Gene3D; 1.20.1530.20; -; 1.
DR Gene3D; 3.40.50.12370; -; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR InterPro; IPR006016; UspA.
DR PANTHER; PTHR43562:SF4; NA(+)_H(+) ANTIPORTER NHAS5; 1.
DR PANTHER; PTHR43562; NAPA-TYPE SODIUM/HYDROGEN ANTIPORTER; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
DR Pfam; PF00582; Usp; 2.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000004344};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 31..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 88..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 116..135
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 147..171
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 177..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 218..244
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 264..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 294..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 327..351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 363..381
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 11..385
FT /note="Cation/H+ exchanger"
FT /evidence="ECO:0000259|Pfam:PF00999"
FT DOMAIN 421..552
FT /note="UspA"
FT /evidence="ECO:0000259|Pfam:PF00582"
FT DOMAIN 560..683
FT /note="UspA"
FT /evidence="ECO:0000259|Pfam:PF00582"
SQ SEQUENCE 689 AA; 74475 MW; 905ED2B9485A67FB CRC64;
MLLQSPIIAF TILLLVIFTV PPIFEKIRLP GLVGLLIAGV VLGENGLNLL NSESETIKLL
SEIGKVYLMF VAGLEIDLGQ FRKTKNRSIG FGSLTFLVPL IAGVIVGRLF NFSWNTSVLI
GSLLASHTLL AYPIVSRLGV VTNEAVTVTI GATIFTDTGA LLVLAVCVGI HGGEFTALSL
ITLLIGLAIY SAVVLFGFDW AGKEFFRRSG DEQGNQFLFI LLALFVASVG AQVIGVEKIV
GAFLAGLAVN DVLGRSPVRE KVEFIGSVLF IPCFFVDMGL LIDIPAFIKT LSSIWLAAAI
VVALIGSKFI AAFLAKLLYR YNTAELLTMW SLSLPQVAAT LAAALVAYKT VNPAGERLIN
EGVLNSVIVL MLVTSIIGPV ITARFASALI VPQTDWAKDK LSTWWQGDSC NVDGQTYHPF
TVVVPLYNPQ TQRYLIEMAA LLARHESGKI VPLAIARGHV QMDDPRLTTA LEQSQQRLQG
VLEISQEFGV EVSPAVRIDD DVALGICRTS REQNANLVVM GWSRNTGIRA RLFGTVIDSV
FWSSHCPVAV TRLLSSPTTI QRILVPVGDL TRQTVGALRF AQILADGNQA EVVLLHVGDR
RTPPTQLDQF KSQLSDIAAQ SKLQVNTAIQ TVIGDDVARV IIHEAKNFDL VVLRSTRYRT
AGGLAVSEVT TQVIKELTCS IVLLGEPHS
//
