ID G6FYB5_9CYAN Unreviewed; 369 AA.
AC G6FYB5;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE SubName: Full=Precorrin-8X methylmutase CbiC/CobH {ECO:0000313|EMBL:EHC09692.1};
GN ORFNames=FJSC11DRAFT_3864 {ECO:0000313|EMBL:EHC09692.1};
OS Fischerella thermalis JSC-11.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Hapalosiphonaceae;
OC Fischerella.
OX NCBI_TaxID=741277 {ECO:0000313|EMBL:EHC09692.1, ECO:0000313|Proteomes:UP000004344};
RN [1] {ECO:0000313|EMBL:EHC09692.1, ECO:0000313|Proteomes:UP000004344}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JSC-11 {ECO:0000313|EMBL:EHC09692.1,
RC ECO:0000313|Proteomes:UP000004344};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Land M.L., Hauser L., Sarkisova S., Bryant D.A., Brown I.,
RA Woyke T.J.;
RT "The draft genome of Fischerella sp. JSC-11.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
CC -!- SIMILARITY: Belongs to the CobH/CbiC family.
CC {ECO:0000256|ARBA:ARBA00009774}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHC09692.1}.
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DR EMBL; AGIZ01000013; EHC09692.1; -; Genomic_DNA.
DR RefSeq; WP_009459179.1; NZ_AGIZ01000013.1.
DR AlphaFoldDB; G6FYB5; -.
DR GeneID; 60767837; -.
DR PATRIC; fig|741277.3.peg.3334; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000004344; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016993; F:precorrin-8X methylmutase activity; IEA:InterPro.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00592; HTH_MerR-like; 1.
DR Gene3D; 1.10.1660.10; -; 1.
DR Gene3D; 3.40.50.10230; Cobalamin biosynthesis CobH/CbiC, precorrin-8X methylmutase; 1.
DR InterPro; IPR003722; Cbl_synth_CobH/CbiC.
DR InterPro; IPR036588; CobH/CbiC_sf.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR000551; MerR-type_HTH_dom.
DR PANTHER; PTHR43588; COBALT-PRECORRIN-8 METHYLMUTASE; 1.
DR PANTHER; PTHR43588:SF1; COBALT-PRECORRIN-8 METHYLMUTASE; 1.
DR Pfam; PF02570; CbiC; 1.
DR Pfam; PF13411; MerR_1; 1.
DR SMART; SM00422; HTH_MERR; 1.
DR SUPFAM; SSF63965; Precorrin-8X methylmutase CbiC/CobH; 1.
DR SUPFAM; SSF46955; Putative DNA-binding domain; 1.
DR PROSITE; PS50937; HTH_MERR_2; 1.
PE 3: Inferred from homology;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Reference proteome {ECO:0000313|Proteomes:UP000004344}.
FT DOMAIN 5..76
FT /note="HTH merR-type"
FT /evidence="ECO:0000259|PROSITE:PS50937"
SQ SEQUENCE 369 AA; 40898 MW; 786C629104766CF7 CRC64;
MKADGLTIKE LTEAVGGGIT PRMVRHYHQL GLLPQPMRSH SNYRLYTETD VIRLQRIVAL
KQQGFQLNHI RQILEVEPPN NPNTNLMLQL QQQYRAVIQQ ISQLRQTASA LEGLLGRDRD
CQIIQAEVLA QLKLIEVETK VGLGELEKLW SGLDAQIHAH PEDFHESLKH VLPDLSARSE
IEQDLISQLV LACGDVSLAS FVKLSQQAIA ASRDALKLGC EIIADIPTVA AALDQTRLFH
LGCRIETLID NPHVTTAVEA EQAFWQQQQW RKKLQQVKKG CIFVVGYAPS VLLSICQAIK
QQQIQPALVI GMPIGFSHAP AAKRQLMRTN GAWIVVEGTI GGGLLAATAL NSLVESVIEK
PDCHCYLSH
//
