ID G6XHF5_9PROT Unreviewed; 342 AA.
AC G6XHF5;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=Putative methylcobalamin:homocysteine methyltransferase {ECO:0000313|EMBL:EHH69613.1};
GN ORFNames=GMO_09210 {ECO:0000313|EMBL:EHH69613.1};
OS Gluconobacter morbifer G707.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Acetobacteraceae; Gluconobacter.
OX NCBI_TaxID=1088869 {ECO:0000313|EMBL:EHH69613.1, ECO:0000313|Proteomes:UP000004949};
RN [1] {ECO:0000313|EMBL:EHH69613.1, ECO:0000313|Proteomes:UP000004949}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=G707 {ECO:0000313|EMBL:EHH69613.1,
RC ECO:0000313|Proteomes:UP000004949};
RA Lee W.-J., Kim E.-K.;
RT "Genome sequence of Gluconobacter morbifer G707, isolated from Drosophila
RT gut.";
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the vitamin-B12 independent methionine synthase
CC family. {ECO:0000256|ARBA:ARBA00009553}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHH69613.1}.
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DR EMBL; AGQV01000001; EHH69613.1; -; Genomic_DNA.
DR RefSeq; WP_008851070.1; NZ_AGQV01000001.1.
DR AlphaFoldDB; G6XHF5; -.
DR STRING; 1088869.GMO_09210; -.
DR PATRIC; fig|1088869.3.peg.927; -.
DR eggNOG; COG0620; Bacteria.
DR OrthoDB; 244285at2; -.
DR Proteomes; UP000004949; Unassembled WGS sequence.
DR GO; GO:0003871; F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0009086; P:methionine biosynthetic process; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd03311; CIMS_C_terminal_like; 1.
DR Gene3D; 3.20.20.210; -; 1.
DR InterPro; IPR002629; Met_Synth_C/arc.
DR InterPro; IPR016456; Met_Synthase_cat.
DR InterPro; IPR038071; UROD/MetE-like_sf.
DR PANTHER; PTHR30519; 5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE; 1.
DR PANTHER; PTHR30519:SF0; 5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE; 1.
DR Pfam; PF01717; Meth_synt_2; 1.
DR PIRSF; PIRSF005632; Met_synth_catalytic_prd; 1.
DR SUPFAM; SSF51726; UROD/MetE-like; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methyltransferase {ECO:0000313|EMBL:EHH69613.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000004949};
KW Transferase {ECO:0000313|EMBL:EHH69613.1};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 5..329
FT /note="Cobalamin-independent methionine synthase MetE C-
FT terminal/archaeal"
FT /evidence="ECO:0000259|Pfam:PF01717"
SQ SEQUENCE 342 AA; 38573 MW; DE91D514D0FEA8E9 CRC64;
MKTLLPTSTA GSLPKPSWLA KPETLWSPWK LQGEELIEGK QDALRLTLDY QDRAGIDIVS
DGEQTRQHFV TTFIEHLGGV DFENRQTVRI RNRYDASVPS VVGAVTREKP VFVEDARFLR
TLTKKPIKWA LPGPMTMIDT LYDGHYRSRE KLAWEFAKIL NQEAKELEAA GVDIIQFDEP
AFNVFFDEVN DWGIAALEKA IEGLKCETAV HICYGYGIKA NIDWKNALGT EWRQYEEIFP
KLQKSNIDLI SLECQNSRVP MDLIELIRGK KVMVGAIDVA TKVIETPEQV ASILRKALQF
VDADKLYPCT NCGMAPLPRR VARAKLGALN AGAEIIRREL SV
//
