ID G7CLU2_MYCT3 Unreviewed; 748 AA.
AC G7CLU2;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=4-alpha-glucanotransferase {ECO:0000256|ARBA:ARBA00020295, ECO:0000256|RuleBase:RU361207};
DE EC=2.4.1.25 {ECO:0000256|ARBA:ARBA00012560, ECO:0000256|RuleBase:RU361207};
DE AltName: Full=Amylomaltase {ECO:0000256|ARBA:ARBA00031423, ECO:0000256|RuleBase:RU361207};
DE AltName: Full=Disproportionating enzyme {ECO:0000256|ARBA:ARBA00031501, ECO:0000256|RuleBase:RU361207};
GN ORFNames=KEK_19923 {ECO:0000313|EMBL:EHI10895.1};
OS Mycolicibacterium thermoresistibile (strain ATCC 19527 / DSM 44167 / CIP
OS 105390 / JCM 6362 / NCTC 10409 / 316) (Mycobacterium thermoresistibile).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=1078020 {ECO:0000313|EMBL:EHI10895.1, ECO:0000313|Proteomes:UP000004915};
RN [1] {ECO:0000313|EMBL:EHI10895.1, ECO:0000313|Proteomes:UP000004915}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19527 / DSM 44167 / CIP 105390 / JCM 6362 / NCTC 10409 /
RC 316 {ECO:0000313|Proteomes:UP000004915};
RG Tuberculosis Structural Genomics Consortium;
RA Ioerger T.R.;
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Transfers a segment of a (1->4)-alpha-D-glucan to a new
CC position in an acceptor, which may be glucose or a (1->4)-alpha-D-
CC glucan.; EC=2.4.1.25; Evidence={ECO:0000256|ARBA:ARBA00000439,
CC ECO:0000256|RuleBase:RU361207};
CC -!- SIMILARITY: Belongs to the disproportionating enzyme family.
CC {ECO:0000256|ARBA:ARBA00005684, ECO:0000256|RuleBase:RU361207}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHI10895.1}.
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DR EMBL; AGVE01000050; EHI10895.1; -; Genomic_DNA.
DR RefSeq; WP_003927453.1; NZ_AGVE01000050.1.
DR AlphaFoldDB; G7CLU2; -.
DR PATRIC; fig|1078020.3.peg.3934; -.
DR eggNOG; COG1640; Bacteria.
DR Proteomes; UP000004915; Unassembled WGS sequence.
DR GO; GO:0004134; F:4-alpha-glucanotransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0102500; F:beta-maltose 4-alpha-glucanotransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR003385; Glyco_hydro_77.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR048458; MalQ_N.
DR NCBIfam; TIGR00217; malQ; 1.
DR PANTHER; PTHR32438; 4-ALPHA-GLUCANOTRANSFERASE DPE1, CHLOROPLASTIC/AMYLOPLASTIC; 1.
DR PANTHER; PTHR32438:SF5; 4-ALPHA-GLUCANOTRANSFERASE DPE1, CHLOROPLASTIC_AMYLOPLASTIC; 1.
DR Pfam; PF02446; Glyco_hydro_77; 1.
DR Pfam; PF21226; MalQ_N; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|RuleBase:RU361207};
KW Glycosyltransferase {ECO:0000256|RuleBase:RU361207};
KW Reference proteome {ECO:0000313|Proteomes:UP000004915};
KW Transferase {ECO:0000256|RuleBase:RU361207, ECO:0000313|EMBL:EHI10895.1}.
FT DOMAIN 69..160
FT /note="MalQ N-terminal beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF21226"
FT REGION 728..748
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 748 AA; 82011 MW; 4B45D25C3EB29118 CRC64;
MTDVAASLAE LAHRHGVATE YVDWRDRPTP VPAATLVAVL AALGVPAATE EQRRASLAAH
DRRYWSRSLP PTVHVRSDRS GSFWVHVPHG SPVRVWIELA DGTVRTDLRQ LENNTPPYDL
DGEPIGEAGF ELPAGLPLGY HRLHMRSTDT AADTTLIVSP GAVALPHRLE SGRAWGPATQ
LYSVISERSW GTGDLTDLTD LAVWSGSRHG ADFLLVNPLH AAAPVTPMEP SPYLPTSRQF
VNPLYLRPEA IPEFAYVRGR ARLRKKRLTV QAHASRSQLI DRDAAWQAKR AALQAVYRVP
RSAGRDMAYT AFRHRAGPRL DDFAVWCALA ERHGPDWRRW PEELRHPRSP AVADFAVRHA
DEVDFHRWLQ WQLDDQLAAA QSAARRIGME LGIMHDLAVG VDAGGADAWA LQDVLAPGVT
AGAPSDEFNQ LGQDWSQPPW RPDRLTECGY EPFRAMVAAV LRHAGGVRID HIIGLFRLWW
IPAGAPPTDG TYVHYDHETM VGIVALEAAR VGAVVVGEDL GTVEPWVRDH LRERGLLGTS
ILWFELDRDS ADPAAPAGPL PAERWREYCL SAVTTHDLPP TPGYLAGAHV RLRAELGLLT
RPAAEEWADD RAKQQAWLAE LRRVGLLDAG VDPADPDAVD DDAVDDDAVD DIVLALHRYL
GRTPSKLLAL GLADAVGDRR IQNQPGTSDE YPNWRVPLSG PDGRRMLLEE VFTDPRAAAL
AEAMRAGAQS RVQSGVQSRP GPGVTGGV
//
