ID G7DU82_MIXOS Unreviewed; 573 AA.
AC G7DU82;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Ceramide glucosyltransferase {ECO:0000256|ARBA:ARBA00019988};
DE EC=2.4.1.80 {ECO:0000256|ARBA:ARBA00012699};
DE AltName: Full=Glucosylceramide synthase {ECO:0000256|ARBA:ARBA00031543};
DE AltName: Full=UDP-glucose ceramide glucosyltransferase {ECO:0000256|ARBA:ARBA00032575};
DE AltName: Full=UDP-glucose:N-acylsphingosine D-glucosyltransferase {ECO:0000256|ARBA:ARBA00031017};
GN Name=Mo00790 {ECO:0000313|EMBL:GAA94142.1};
GN ORFNames=E5Q_00790 {ECO:0000313|EMBL:GAA94142.1};
OS Mixia osmundae (strain CBS 9802 / IAM 14324 / JCM 22182 / KY 12970).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina; Mixiomycetes;
OC Mixiales; Mixiaceae; Mixia.
OX NCBI_TaxID=764103 {ECO:0000313|EMBL:GAA94142.1, ECO:0000313|Proteomes:UP000009131};
RN [1] {ECO:0000313|Proteomes:UP000009131}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 9802 / IAM 14324 / JCM 22182 / KY 12970
RC {ECO:0000313|Proteomes:UP000009131};
RX PubMed=21478649; DOI=10.2323/jgam.57.63;
RA Nishida H., Nagatsuka Y., Sugiyama J.;
RT "Draft genome sequencing of the enigmatic basidiomycete Mixia osmundae.";
RL J. Gen. Appl. Microbiol. 57:63-67(2011).
CC -!- PATHWAY: Lipid metabolism; sphingolipid metabolism.
CC {ECO:0000256|ARBA:ARBA00004760}.
CC -!- PATHWAY: Sphingolipid metabolism. {ECO:0000256|ARBA:ARBA00004991}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 2 family.
CC {ECO:0000256|ARBA:ARBA00006739}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uS14 family.
CC {ECO:0000256|ARBA:ARBA00009083}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAA94142.1}.
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DR EMBL; BABT02000028; GAA94142.1; -; Genomic_DNA.
DR AlphaFoldDB; G7DU82; -.
DR STRING; 764103.G7DU82; -.
DR eggNOG; KOG1741; Eukaryota.
DR eggNOG; KOG2547; Eukaryota.
DR HOGENOM; CLU_030898_1_0_1; -.
DR InParanoid; G7DU82; -.
DR UniPathway; UPA00222; -.
DR Proteomes; UP000009131; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0008120; F:ceramide glucosyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0102769; F:dihydroceramide glucosyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006665; P:sphingolipid metabolic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR CDD; cd02520; Glucosylceramide_synthase; 1.
DR Gene3D; 1.10.287.1480; -; 1.
DR InterPro; IPR025993; Ceramide_glucosylTrfase.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR InterPro; IPR001209; Ribosomal_uS14.
DR PANTHER; PTHR12726; CERAMIDE GLUCOSYLTRANSFERASE; 1.
DR PANTHER; PTHR12726:SF0; CERAMIDE GLUCOSYLTRANSFERASE; 1.
DR Pfam; PF13506; Glyco_transf_21; 1.
DR Pfam; PF00253; Ribosomal_S14; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000009131};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274};
KW Ribosomal protein {ECO:0000256|ARBA:ARBA00022980};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
SQ SEQUENCE 573 AA; 63850 MW; 9E699EB74FBE6D03 CRC64;
MVKQYPARVL RDIKRREAFA STELLRKAYL YVARNEMLPV QIRTQAQLSL QSPAIFSTAS
RPSAPKNRCV ETGRGRGVLG KIGLCRHQFK LKATRGELNG WSKASCFVME ERQSAATFSW
PLAAQLACVV WVSAMYAIGN LGRYVARSRY TGQFEQPKPT TAQPGVTILR PLRGLDCNLY
DNLEASFRQD YADKEIICSV ASSADQAIPI VNDLIAKYPA VKAKLLIGEQ DVGVNPKINN
LVRSYHEATH DLLWILDANV LMDVGALTRA VQALQSTSGS RSIGLVHHVP FALMPDVSLG
ARIEQVFLCT THAKMYLAIN FLRVDSCVMG KSTLFRRSDL NVATTKRAAR SKSTNAATGL
EAFGRYLGED NMIGSAIWHD LGYRHAMSVD VAGNTIGSMA LSSYFWRRVR WIRVRKYMVT
ASTLVEPLTE SVVCGIMIAY GFNRLLPIWL VLLLHFGSWY ATDVAVYHAL QRAAPYESGR
AAHDGPGVAF FRAWILRELS ALPIWIFAMA GDRVGWRDDG KQYRVRSNGE VEEAAAEPPG
QLQKGLLWLW RKGPLHGRRS GYRVLPVDTP TIR
//
