ID G7DVV8_MIXOS Unreviewed; 486 AA.
AC G7DVV8;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=phenylalanine--tRNA ligase {ECO:0000256|ARBA:ARBA00012814};
DE EC=6.1.1.20 {ECO:0000256|ARBA:ARBA00012814};
DE AltName: Full=Phenylalanyl-tRNA synthetase alpha subunit {ECO:0000256|ARBA:ARBA00030612};
GN Name=Mo01371 {ECO:0000313|EMBL:GAA94718.1};
GN ORFNames=E5Q_01371 {ECO:0000313|EMBL:GAA94718.1};
OS Mixia osmundae (strain CBS 9802 / IAM 14324 / JCM 22182 / KY 12970).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina; Mixiomycetes;
OC Mixiales; Mixiaceae; Mixia.
OX NCBI_TaxID=764103 {ECO:0000313|EMBL:GAA94718.1, ECO:0000313|Proteomes:UP000009131};
RN [1] {ECO:0000313|Proteomes:UP000009131}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 9802 / IAM 14324 / JCM 22182 / KY 12970
RC {ECO:0000313|Proteomes:UP000009131};
RX PubMed=21478649; DOI=10.2323/jgam.57.63;
RA Nishida H., Nagatsuka Y., Sugiyama J.;
RT "Draft genome sequencing of the enigmatic basidiomycete Mixia osmundae.";
RL J. Gen. Appl. Microbiol. 57:63-67(2011).
CC -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.
CC Phe-tRNA synthetase alpha subunit type 2 subfamily.
CC {ECO:0000256|ARBA:ARBA00006703}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAA94718.1}.
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DR EMBL; BABT02000046; GAA94718.1; -; Genomic_DNA.
DR RefSeq; XP_014568170.1; XM_014712684.1.
DR AlphaFoldDB; G7DVV8; -.
DR STRING; 764103.G7DVV8; -.
DR GeneID; 26267199; -.
DR eggNOG; KOG2784; Eukaryota.
DR HOGENOM; CLU_025086_2_0_1; -.
DR InParanoid; G7DVV8; -.
DR OMA; QIEGWVM; -.
DR OrthoDB; 4619at2759; -.
DR Proteomes; UP000009131; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004826; F:phenylalanine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0000049; F:tRNA binding; IEA:InterPro.
DR GO; GO:0006432; P:phenylalanyl-tRNA aminoacylation; IEA:InterPro.
DR CDD; cd00496; PheRS_alpha_core; 1.
DR Gene3D; 1.10.10.2320; -; 1.
DR Gene3D; 1.10.10.2330; -; 1.
DR Gene3D; 3.30.1370.240; -; 1.
DR InterPro; IPR006195; aa-tRNA-synth_II.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR004529; Phe-tRNA-synth_IIc_asu.
DR InterPro; IPR002319; Phenylalanyl-tRNA_Synthase.
DR InterPro; IPR040725; PheRS_DBD3.
DR NCBIfam; TIGR00468; pheS; 1.
DR PANTHER; PTHR11538:SF40; PHENYLALANINE--TRNA LIGASE ALPHA SUBUNIT; 1.
DR PANTHER; PTHR11538; PHENYLALANYL-TRNA SYNTHETASE; 1.
DR Pfam; PF18553; PheRS_DBD3; 1.
DR Pfam; PF01409; tRNA-synt_2d; 1.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000009131}.
FT DOMAIN 219..474
FT /note="Aminoacyl-transfer RNA synthetases class-II family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50862"
SQ SEQUENCE 486 AA; 54245 MW; 843B6E10C271336D CRC64;
MTSQVAQTIL DFLDQNASIP DTRTLGLDAA AVRAALTSLV DKQMVLMESH AQEEAVLSAE
GEEVTEKGSP EWRLWQVLAT GPQTAKQLQS TLGPDTAKVG QLNAFKKKWI KKDGDGFAQA
LSDVPDQVRS DLQALKNGQP LPSTVASEYR KRKLTAIKRT AYQSVSKGPK FSTKIAKLET
DLTAEMLQSG AWKTAEFKPF NFDAEGMPPA AGALHPLLKV REEFRNIFFE MGFSEMPTNQ
FVESCFWNFD ALFVPQQHPA RELQDTFYVK DPASTDDFPE DYLAKVRKVH ESGGYGSIGY
RSPWKQSDTE RLVLRTHTTA ISANMLYKLA NQPGGFKPTK LFSIDRVFRN EAVDATHLAE
FHQVEGVVAD YNLTLGDLIG FMDVFFAKMG VKNLRFKPAF NPYTEPSLEI FSYHAGLGKW
VEIGNSGMFR PEMLEPMGLP KDVRALGWGL SLERPTMIKY GISNIRDLVG HKVPIEMVEK
SAAVRF
//
