ID G7DXV1_MIXOS Unreviewed; 495 AA.
AC G7DXV1;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=cysteine synthase {ECO:0000256|ARBA:ARBA00012681};
DE EC=2.5.1.47 {ECO:0000256|ARBA:ARBA00012681};
GN Name=Mo02065 {ECO:0000313|EMBL:GAA95411.1};
GN ORFNames=E5Q_02065 {ECO:0000313|EMBL:GAA95411.1};
OS Mixia osmundae (strain CBS 9802 / IAM 14324 / JCM 22182 / KY 12970).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina; Mixiomycetes;
OC Mixiales; Mixiaceae; Mixia.
OX NCBI_TaxID=764103 {ECO:0000313|EMBL:GAA95411.1, ECO:0000313|Proteomes:UP000009131};
RN [1] {ECO:0000313|Proteomes:UP000009131}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 9802 / IAM 14324 / JCM 22182 / KY 12970
RC {ECO:0000313|Proteomes:UP000009131};
RX PubMed=21478649; DOI=10.2323/jgam.57.63;
RA Nishida H., Nagatsuka Y., Sugiyama J.;
RT "Draft genome sequencing of the enigmatic basidiomycete Mixia osmundae.";
RL J. Gen. Appl. Microbiol. 57:63-67(2011).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the cysteine synthase/cystathionine beta-
CC synthase family. {ECO:0000256|ARBA:ARBA00007103}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAA95411.1}.
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DR EMBL; BABT02000062; GAA95411.1; -; Genomic_DNA.
DR RefSeq; XP_014569931.1; XM_014714445.1.
DR AlphaFoldDB; G7DXV1; -.
DR STRING; 764103.G7DXV1; -.
DR GeneID; 26262793; -.
DR eggNOG; KOG1481; Eukaryota.
DR HOGENOM; CLU_021018_1_0_1; -.
DR InParanoid; G7DXV1; -.
DR OMA; WMADYGF; -.
DR OrthoDB; 852805at2759; -.
DR Proteomes; UP000009131; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
DR CDD; cd01561; CBS_like; 1.
DR Gene3D; 3.40.50.1100; -; 4.
DR InterPro; IPR001216; P-phosphate_BS.
DR InterPro; IPR001926; TrpB-like_PALP.
DR InterPro; IPR036052; TrpB-like_PALP_sf.
DR PANTHER; PTHR10314; CYSTATHIONINE BETA-SYNTHASE; 1.
DR PANTHER; PTHR10314:SF35; MITOCHONDRIAL CYSTEINE SYNTHASE-RELATED; 1.
DR Pfam; PF00291; PALP; 1.
DR SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
DR PROSITE; PS00901; CYS_SYNTHASE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009131};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 40..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 89..445
FT /note="Tryptophan synthase beta chain-like PALP"
FT /evidence="ECO:0000259|Pfam:PF00291"
SQ SEQUENCE 495 AA; 53938 MW; B5B5795DD7AB3C38 CRC64;
MSSRYAGIHT NLSVPAWLSP TRWSHSFQEV LNRLGLSRDL LLGLSIGITF SLTSTGLALW
ARDRWKRMLR QRQTWRPIEI RSSEIVDGVT GLIGNTPLVR IKSLSELTGV DILGKAEFLN
PAGSPKDRVA LELIQSAEDA GLLHPNTDSC IYEGTVGSTG ISIATVARAK GYQACIIMPD
DVAKEKSLLL EKLGAQVQKV RPVSIVDKQH YVNLARSRAL HHGLTQLIGP DPAIDPTPAM
GYRKAQPRSD EVVTTDADHD AVFHENTPKG HEDDLEKLPR GFFADQFENL ANYEAHLKTT
GPEIWRQTNG EIDAFVAGAG TGGTLAGVGR YLKGYDDSIK LVLADPQGSG LFNKVKQGVM
YASTEAEGKR RRHQVDSIVE GIGINRITRN FDQVVSFIDD AISVTDAEAV AMSRHLAYND
GLFLGSSSAV NLVAAVKYAK TLKGALLKTV SEGRERSVIV TILCDSGARH LSRFWNDEYL
TSMGIPITAS LEGII
//
