ID G7E816_MIXOS Unreviewed; 707 AA.
AC G7E816;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 24-JAN-2024, entry version 51.
DE RecName: Full=DNA mismatch repair protein S5 domain-containing protein {ECO:0000259|SMART:SM01340};
GN Name=Mo05664 {ECO:0000313|EMBL:GAA98976.1};
GN ORFNames=E5Q_05664 {ECO:0000313|EMBL:GAA98976.1};
OS Mixia osmundae (strain CBS 9802 / IAM 14324 / JCM 22182 / KY 12970).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina; Mixiomycetes;
OC Mixiales; Mixiaceae; Mixia.
OX NCBI_TaxID=764103 {ECO:0000313|EMBL:GAA98976.1, ECO:0000313|Proteomes:UP000009131};
RN [1] {ECO:0000313|Proteomes:UP000009131}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 9802 / IAM 14324 / JCM 22182 / KY 12970
RC {ECO:0000313|Proteomes:UP000009131};
RX PubMed=21478649; DOI=10.2323/jgam.57.63;
RA Nishida H., Nagatsuka Y., Sugiyama J.;
RT "Draft genome sequencing of the enigmatic basidiomycete Mixia osmundae.";
RL J. Gen. Appl. Microbiol. 57:63-67(2011).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutL/HexB family.
CC {ECO:0000256|ARBA:ARBA00006082}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAA98976.1}.
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DR EMBL; BABT02000165; GAA98976.1; -; Genomic_DNA.
DR AlphaFoldDB; G7E816; -.
DR STRING; 764103.G7E816; -.
DR eggNOG; KOG1979; Eukaryota.
DR HOGENOM; CLU_004131_2_0_1; -.
DR InParanoid; G7E816; -.
DR Proteomes; UP000009131; Unassembled WGS sequence.
DR GO; GO:0032300; C:mismatch repair complex; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0061982; P:meiosis I cell cycle process; IEA:UniProt.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR CDD; cd16926; HATPase_MutL-MLH-PMS-like; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR014762; DNA_mismatch_repair_CS.
DR InterPro; IPR013507; DNA_mismatch_S5_2-like.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR032189; Mlh1_C.
DR InterPro; IPR002099; MutL/Mlh/PMS.
DR InterPro; IPR038973; MutL/Mlh/Pms-like.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR NCBIfam; TIGR00585; mutl; 1.
DR PANTHER; PTHR10073; DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL; 1.
DR PANTHER; PTHR10073:SF12; DNA MISMATCH REPAIR PROTEIN MLH1; 1.
DR Pfam; PF01119; DNA_mis_repair; 1.
DR Pfam; PF13589; HATPase_c_3; 1.
DR Pfam; PF16413; Mlh1_C; 1.
DR SMART; SM01340; DNA_mis_repair; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR PROSITE; PS00058; DNA_MISMATCH_REPAIR_1; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000009131}.
FT DOMAIN 257..376
FT /note="DNA mismatch repair protein S5"
FT /evidence="ECO:0000259|SMART:SM01340"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 707 AA; 77985 MW; E119D3AB700EA504 CRC64;
MSEPATTSGQ AEPAPLLDEP RPIRQLSESV VNRIAAGEVV QRPANAVKEL LENALDAGAT
TVRVEVKDGG LKRIVIVDDG LGIRHEDLPL LCQRFATSKI STFDDLSSLS SYGFRGEALA
SISHVAHLTV VTKTRHDLAG WKAKYADGIL VPHSSSDTSS EPKRAAAVNG TQFIIEDLFY
NIPTRLRALK SASDEYARIL DVLGKYAIQN ASVSISCRKV GAREWDLNTG LPASVSILSD
ATSSQTQQDL SQQSDVIGGI YGQAIKKELV EVSLQEDTLA LSAHGWFSGL NFSAKKAVYV
IFVNNRLVES RSIRKSLEIF YAPLLPKGGF PFVYISLMLD PATIDVNVHP TKSEVGFMNE
DDISDALCTA LEAKLEESRQ SRGFKVISAP RNSANTDPTQ QDARLLSRNV PQHQIRTDHQ
ARTLTSMLVT DGQALERSQL PTQAPIEARK GKITESACNL TSIQELRAEV GDSKHAGASA
IFADHTFVGV VDSDRGLSLI QHATKLYIAR HDECLEELFY QLGLRQFGQM GRMLLDPPPK
LSELIQIAVD HEPQVTNAHL SPDEIKERAT RRWLERRDMV AEYFAIDLDE LDRVVSVPLI
LPGYTPPLEN LPRFFLHGAV QIEWTSERGC FASMLRSIAR MSLPLPPELE TMPTGVSLPP
ETAYRWQIEH VLFPALKAYL VAPVSLRDQG IIHVASLSNL YKVFERC
//
