ID G7LGA4_MEDTR Unreviewed; 805 AA.
AC G7LGA4;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=LRR and NB-ARC domain disease resistance protein {ECO:0000313|EMBL:AET04028.1};
DE SubName: Full=Putative P-loop containing nucleoside triphosphate hydrolase, leucine-rich repeat domain, L {ECO:0000313|EMBL:RHN42216.1};
GN Name=11419017 {ECO:0000313|EnsemblPlants:AET04028};
GN OrderedLocusNames=MTR_8g079360 {ECO:0000313|EMBL:AET04028.1};
GN ORFNames=MtrunA17_Chr8g0374471 {ECO:0000313|EMBL:RHN42216.1};
OS Medicago truncatula (Barrel medic) (Medicago tribuloides).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Trifolieae; Medicago.
OX NCBI_TaxID=3880 {ECO:0000313|EMBL:AET04028.1, ECO:0000313|Proteomes:UP000002051};
RN [1] {ECO:0000313|EMBL:AET04028.1, ECO:0000313|Proteomes:UP000002051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A17 {ECO:0000313|EMBL:AET04028.1}, and cv. Jemalong A17
RC {ECO:0000313|EnsemblPlants:AET04028,
RC ECO:0000313|Proteomes:UP000002051};
RX PubMed=22089132; DOI=10.1038/nature10625;
RA Young N.D., Debelle F., Oldroyd G.E., Geurts R., Cannon S.B., Udvardi M.K.,
RA Benedito V.A., Mayer K.F., Gouzy J., Schoof H., Van de Peer Y., Proost S.,
RA Cook D.R., Meyers B.C., Spannagl M., Cheung F., De Mita S.,
RA Krishnakumar V., Gundlach H., Zhou S., Mudge J., Bharti A.K., Murray J.D.,
RA Naoumkina M.A., Rosen B., Silverstein K.A., Tang H., Rombauts S.,
RA Zhao P.X., Zhou P., Barbe V., Bardou P., Bechner M., Bellec A., Berger A.,
RA Berges H., Bidwell S., Bisseling T., Choisne N., Couloux A., Denny R.,
RA Deshpande S., Dai X., Doyle J.J., Dudez A.M., Farmer A.D., Fouteau S.,
RA Franken C., Gibelin C., Gish J., Goldstein S., Gonzalez A.J., Green P.J.,
RA Hallab A., Hartog M., Hua A., Humphray S.J., Jeong D.H., Jing Y.,
RA Jocker A., Kenton S.M., Kim D.J., Klee K., Lai H., Lang C., Lin S.,
RA Macmil S.L., Magdelenat G., Matthews L., McCorrison J., Monaghan E.L.,
RA Mun J.H., Najar F.Z., Nicholson C., Noirot C., O'Bleness M., Paule C.R.,
RA Poulain J., Prion F., Qin B., Qu C., Retzel E.F., Riddle C., Sallet E.,
RA Samain S., Samson N., Sanders I., Saurat O., Scarpelli C., Schiex T.,
RA Segurens B., Severin A.J., Sherrier D.J., Shi R., Sims S., Singer S.R.,
RA Sinharoy S., Sterck L., Viollet A., Wang B.B., Wang K., Wang M., Wang X.,
RA Warfsmann J., Weissenbach J., White D.D., White J.D., Wiley G.B.,
RA Wincker P., Xing Y., Yang L., Yao Z., Ying F., Zhai J., Zhou L., Zuber A.,
RA Denarie J., Dixon R.A., May G.D., Schwartz D.C., Rogers J., Quetier F.,
RA Town C.D., Roe B.A.;
RT "The Medicago genome provides insight into the evolution of rhizobial
RT symbioses.";
RL Nature 480:520-524(2011).
RN [2] {ECO:0000313|EMBL:AET04028.1, ECO:0000313|Proteomes:UP000002051}
RP GENOME REANNOTATION.
RC STRAIN=cv. Jemalong A17 {ECO:0000313|EnsemblPlants:AET04028,
RC ECO:0000313|Proteomes:UP000002051};
RX PubMed=24767513; DOI=10.1186/1471-2164-15-312;
RA Tang H., Krishnakumar V., Bidwell S., Rosen B., Chan A., Zhou S.,
RA Gentzbittel L., Childs K.L., Yandell M., Gundlach H., Mayer K.F.,
RA Schwartz D.C., Town C.D.;
RT "An improved genome release (version Mt4.0) for the model legume Medicago
RT truncatula.";
RL BMC Genomics 15:312-312(2014).
RN [3] {ECO:0000313|EnsemblPlants:AET04028}
RP IDENTIFICATION.
RC STRAIN=cv. Jemalong A17 {ECO:0000313|EnsemblPlants:AET04028};
RG EnsemblPlants;
RL Submitted (APR-2015) to UniProtKB.
RN [4] {ECO:0000313|EMBL:RHN42216.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:RHN42216.1};
RA Pecrix Y., Gamas P., Carrere S.;
RT "Whole-genome landscape of Medicago truncatula symbiotic genes.";
RL Nat. Plants 0:0-0(2018).
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DR EMBL; CM001224; AET04028.1; -; Genomic_DNA.
DR EMBL; PSQE01000008; RHN42216.1; -; Genomic_DNA.
DR RefSeq; XP_003629552.1; XM_003629504.2.
DR AlphaFoldDB; G7LGA4; -.
DR PaxDb; 3880-AET04028; -.
DR EnsemblPlants; AET04028; AET04028; MTR_8g079360.
DR GeneID; 120575717; -.
DR Gramene; AET04028; AET04028; MTR_8g079360.
DR KEGG; mtr:120575717; -.
DR eggNOG; ENOG502QSSA; Eukaryota.
DR HOGENOM; CLU_012216_0_0_1; -.
DR OMA; CIKQREY; -.
DR OrthoDB; 1208714at2759; -.
DR Proteomes; UP000002051; Chromosome 8.
DR Proteomes; UP000265566; Chromosome 8.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0050832; P:defense response to fungus; IEA:InterPro.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039203; RGA2/3-like.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR36766; PLANT BROAD-SPECTRUM MILDEW RESISTANCE PROTEIN RPW8; 1.
DR PANTHER; PTHR36766:SF3; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52047; RNI-like; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:RHN42216.1};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000002051}.
FT DOMAIN 152..365
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 805 AA; 91664 MW; 4B095CF110910601 CRC64;
MSSATHIITL TTRFQFNDVL NKISQILQKA QKNQSSRRSL RLILKDLSPV VQDIKQYNDH
LDHPREEINS LIEENDAGES ACTCSSENDS YGYVVEENQS LTVNDVEETL YKTREILELL
NHEFNEDGQL FKRPFNVPEN QKFTVGLDIP FSKLKMELLR GGSSTLVLTG LGGLGKTTLA
TKLCWDEEVN GKFKENIIFV TFSKTPMLKT IVERIHQHCG YPVPEFQSDE DAVNRLGLLL
KKVEGSPLLL VLDDVWPISE PLVEKIQFQI SDFKILVTSR VAFPRFSTTC ILKPLAHEEA
VTLFHHYAQM EKNSSDIINK NLVEKVVRSC QGLPLTIKVI ATSLKNRPRD MWRKIGKELS
QGHSILDSNT DLLTRLQKIF DVLEDNPTIM ECFMDIALFP EDHRIPVAAL VDMWAELYRL
DDNGIQAMEI INKLGIMNLA NVIIPRKNAS DTDNNNYNNH FIILHDILRE LGIYQSAKEP
FEQRKRLIID INKNKSGLAE KQQGLMTCIL SKFMRLCVKR NPQQLTARIL SVSADETCAF
DWSQMEPAQV EVLILNLHTK QYSLPEWIAK MSKLRVLIIT NYDFHPSKLN NIELLGSLQN
LERIRLERIY VPSFGTLKNL KKLSLYMCNT ILAFEKGSIL ISDAFPNLEE LNIDYCKDLV
VLPIGICDIF LLKKLRVTNC HKLSSLPQDI GKLENLELLS LSSCTDLEAI PTSIGKLLNL
KHLDISNCIS LSSLPEEFGN LCNLKNLDMA SCASIELPFS VVNLQNLKTI TCDEETAATW
EDFQHMLPNM KIEVLHVDVN LNWLL
//
