ID G7M1B5_9CLOT Unreviewed; 506 AA.
AC G7M1B5;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=LexA repressor {ECO:0000313|EMBL:EHI99991.1};
GN ORFNames=CDLVIII_3431 {ECO:0000313|EMBL:EHI99991.1};
OS Clostridium sp. DL-VIII.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=641107 {ECO:0000313|EMBL:EHI99991.1, ECO:0000313|Proteomes:UP000005106};
RN [1] {ECO:0000313|EMBL:EHI99991.1, ECO:0000313|Proteomes:UP000005106}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DL-VIII {ECO:0000313|EMBL:EHI99991.1,
RC ECO:0000313|Proteomes:UP000005106};
RX PubMed=23929491;
RA Taghavi S., Izquierdo J.A., van der Lelie D.;
RT "Complete Genome Sequence of Clostridium sp. Strain DL-VIII, a Novel
RT Solventogenic Clostridium Species Isolated from Anaerobic Sludge.";
RL Genome Announc. 1:e00605-e00613(2013).
CC -!- SIMILARITY: Belongs to the peptidase S24 family.
CC {ECO:0000256|ARBA:ARBA00007484, ECO:0000256|RuleBase:RU003991}.
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DR EMBL; CM001240; EHI99991.1; -; Genomic_DNA.
DR RefSeq; WP_009170652.1; NZ_CM001240.1.
DR AlphaFoldDB; G7M1B5; -.
DR STRING; 641107.CDLVIII_3431; -.
DR eggNOG; COG1974; Bacteria.
DR HOGENOM; CLU_018674_0_0_9; -.
DR Proteomes; UP000005106; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0009432; P:SOS response; IEA:UniProtKB-KW.
DR CDD; cd06529; S24_LexA-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.10.109.10; Umud Fragment, subunit A; 1.
DR InterPro; IPR039418; LexA-like.
DR InterPro; IPR036286; LexA/Signal_pep-like_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR006197; Peptidase_S24_LexA.
DR InterPro; IPR015927; Peptidase_S24_S26A/B/C.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR33516; LEXA REPRESSOR; 1.
DR PANTHER; PTHR33516:SF13; PROPHAGE REPRESSOR COHE-RELATED; 1.
DR Pfam; PF00717; Peptidase_S24; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR PRINTS; PR00726; LEXASERPTASE.
DR SUPFAM; SSF51306; LexA/Signal peptidase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Autocatalytic cleavage {ECO:0000256|ARBA:ARBA00022813,
KW ECO:0000256|RuleBase:RU003991}; DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU003991};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protease {ECO:0000256|ARBA:ARBA00022825};
KW Reference proteome {ECO:0000313|Proteomes:UP000005106};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825};
KW SOS mutagenesis {ECO:0000256|ARBA:ARBA00023199};
KW SOS response {ECO:0000256|ARBA:ARBA00023236}.
FT DOMAIN 4..265
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|Pfam:PF00580"
FT DOMAIN 385..500
FT /note="Peptidase S24/S26A/S26B/S26C"
FT /evidence="ECO:0000259|Pfam:PF00717"
SQ SEQUENCE 506 AA; 58787 MW; F4FB82FAD0F55AEC CRC64;
MEFNKEQKKI INYKPHGHLL IKGEKLTGKT TIIINKIPML LNHYCIEKND KILIAAYDEQ
HLRHISYIYD NIESEKYHQN SFFDEDNSDK LEIRTIESLI IYYFNKYKKD NSIEITMASA
EECEKQLKDS MEIIKKKYEK NKFDLLDYEN IEFVKEEIAW IKSCSYLNIN DYQTANRIGR
INRLNNDARI LRKNSKQRQA IYEVLDEYNK KLGMLNKVDL QDMALLALES AQGMQTKKYT
HIVIDDCEKL TRVQLEFLKA LYNDKVYSSL NFTLNTDSNM TLNAWITKGR SFASLGYDMK
GKSISLKRTF AEKSNENKII AKEMNHDNLK KNTSSNKSFV LDTIEYIDLK HNVSHRFIKD
SGNIDEIYIE ANGIDEKVED VISIPLFNEI AAGNPILIND EVDENYYLPK EWIKNTKGTF
MLKVKGDSMI NKNINDGDYV IISNQSYPNV KDIVAVDIEG EATLKTYKII NGKITLMPEN
EKYDPIIIED QQFSFLGVAI GLVKNS
//
