ID   G7M9G0_9CLOT            Unreviewed;       503 AA.
AC   G7M9G0;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   SubName: Full=Metallophosphoesterase {ECO:0000313|EMBL:EHJ02177.1};
GN   ORFNames=CDLVIII_5709 {ECO:0000313|EMBL:EHJ02177.1};
OS   Clostridium sp. DL-VIII.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=641107 {ECO:0000313|EMBL:EHJ02177.1, ECO:0000313|Proteomes:UP000005106};
RN   [1] {ECO:0000313|EMBL:EHJ02177.1, ECO:0000313|Proteomes:UP000005106}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DL-VIII {ECO:0000313|EMBL:EHJ02177.1,
RC   ECO:0000313|Proteomes:UP000005106};
RX   PubMed=23929491;
RA   Taghavi S., Izquierdo J.A., van der Lelie D.;
RT   "Complete Genome Sequence of Clostridium sp. Strain DL-VIII, a Novel
RT   Solventogenic Clostridium Species Isolated from Anaerobic Sludge.";
RL   Genome Announc. 1:e00605-e00613(2013).
CC   -!- SIMILARITY: Belongs to the 5'-nucleotidase family.
CC       {ECO:0000256|RuleBase:RU362119}.
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DR   EMBL; CM001240; EHJ02177.1; -; Genomic_DNA.
DR   RefSeq; WP_009172813.1; NZ_CM001240.1.
DR   AlphaFoldDB; G7M9G0; -.
DR   STRING; 641107.CDLVIII_5709; -.
DR   eggNOG; COG0737; Bacteria.
DR   HOGENOM; CLU_005854_4_4_9; -.
DR   Proteomes; UP000005106; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0009166; P:nucleotide catabolic process; IEA:InterPro.
DR   Gene3D; 3.60.21.10; -; 1.
DR   Gene3D; 3.90.780.10; 5'-Nucleotidase, C-terminal domain; 1.
DR   InterPro; IPR008334; 5'-Nucleotdase_C.
DR   InterPro; IPR036907; 5'-Nucleotdase_C_sf.
DR   InterPro; IPR006179; 5_nucleotidase/apyrase.
DR   InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR   InterPro; IPR029052; Metallo-depent_PP-like.
DR   PANTHER; PTHR11575:SF6; 2',3'-CYCLIC-NUCLEOTIDE 2'-PHOSPHODIESTERASE_3'-NUCLEOTIDASE; 1.
DR   PANTHER; PTHR11575; 5'-NUCLEOTIDASE-RELATED; 1.
DR   Pfam; PF02872; 5_nucleotid_C; 1.
DR   Pfam; PF00149; Metallophos; 1.
DR   PRINTS; PR01607; APYRASEFAMLY.
DR   SUPFAM; SSF55816; 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain; 1.
DR   SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW   Hydrolase {ECO:0000256|RuleBase:RU362119};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362119};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005106}.
FT   DOMAIN          4..227
FT                   /note="Calcineurin-like phosphoesterase"
FT                   /evidence="ECO:0000259|Pfam:PF00149"
FT   DOMAIN          308..464
FT                   /note="5'-Nucleotidase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02872"
SQ   SEQUENCE   503 AA;  57925 MW;  58FE02F3A929DBA9 CRC64;
     MKTLKIYFTS DMHGFVYPTD YTDNIQKPIG ILNTINSFTK DKNTLVIDGG DTIQGSPFTT
     YLSKIKLKEH PISKVMNEGG YDFITLGNHD FNYGYDYLKK YLKEFKGQCI CCNVKDKTGE
     ISILPYAIKK MENGLVVGII GVTTEFINVW EQSHNLENFS IEDTLSSLEK QYNEIKYKVD
     VLIGVYHGGF ERDLDTNKIL SNTTENLGDR ICSKFKFDIL LTGHQHTSIS GRRLYGTYIV
     QTPANGQGFI EINLQYENSI SEISSSIRIP KIKPNKKMFK ELLPMEKEVQ KWLDTPVGYL
     DVDLIPKHHL NMALEGSIIA NFINFIQINE SRADISCTSF ANSIKGFKKE VTVRDIVSTY
     VYPNTLVVLE ITGEILKKAL LRTCEYFNYD GKEISVSETF LKPKVEHYNY DYFSNIQYCF
     RLYENNKHKL EYVRLSGKDI GDEEKLTIVM NNYRASGAGG YEFYKNCTVV KEIQLEMTEI
     IINYFEKYKN IIVDKNKYVE VVT
//