ID G7MDL0_MACMU Unreviewed; 437 AA.
AC G7MDL0;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=Sorting nexin-27 {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=EGK_01266 {ECO:0000313|EMBL:EHH15207.1};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|EMBL:EHH15207.1};
RN [1] {ECO:0000313|EMBL:EHH15207.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CR-5 {ECO:0000313|EMBL:EHH15207.1};
RX PubMed=22002653; DOI=10.1038/nbt.1992;
RA Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT "Genome sequencing and comparison of two nonhuman primate animal models,
RT the cynomolgus and Chinese rhesus macaques.";
RL Nat. Biotechnol. 29:1019-1023(2011).
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DR EMBL; CM001253; EHH15207.1; -; Genomic_DNA.
DR AlphaFoldDB; G7MDL0; -.
DR Proteomes; UP000013456; Chromosome 1.
DR GO; GO:0005768; C:endosome; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProt.
DR CDD; cd13338; FERM-like_C_SNX27; 1.
DR CDD; cd01777; FERM_F1_SNX27; 1.
DR CDD; cd06886; PX_SNX27; 1.
DR Gene3D; 1.20.80.60; -; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR000159; RA_dom.
DR InterPro; IPR037831; SNX17/27/31-like.
DR InterPro; IPR037827; SNX27_FERM-like_dom.
DR InterPro; IPR037833; SNX27_PX.
DR InterPro; IPR037835; SNX27_RA.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR12431; SORTING NEXIN 17 AND 27; 1.
DR PANTHER; PTHR12431:SF19; SORTING NEXIN-27; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF00788; RA; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS50200; RA; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Transport {ECO:0000256|ARBA:ARBA00022927}.
FT DOMAIN 57..165
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT DOMAIN 169..258
FT /note="Ras-associating"
FT /evidence="ECO:0000259|PROSITE:PS50200"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EHH15207.1"
FT NON_TER 437
FT /evidence="ECO:0000313|EMBL:EHH15207.1"
SQ SEQUENCE 437 AA; 51112 MW; FE9A81EA9D34DA22 CRC64;
NHVNVEGATH KQVVDLIRAG EKELILTVLS VPPHEADNLD PSDDSLGQSF YDYTEKQAVP
ISVPRYKHVE QNGEKFVVYN VYMAGRQLCS KRYREFAILH QNLKREFANF TFPRLPGKWP
FSLSEQQLDA RRRGLEEYLE KVCSIRVIGE SDIMQEFLSE SDENYNGVSD VELRVALPDG
TTVTVRVKKN STTDQVYQAI AAKVGMDSTT VNYFALFEVI NHSFVRKLAP NEFPHKLYIQ
NYTSAVPGTC LTIRKWLFTT EEEILLNDND LAVTYFFHQA VDDVKKGYIK AEEKSYQLQK
LYEQRKMVMY LNMLRTCEGY NEIIFPHCAC DSRRKGHVIT AISITHFKLH ACTEEGQLEN
QVIAFEWDEM QRWDTDEEGM AFCFEYARGE KKPRWVKIFT PYFNYMHECF ERVFCELKWR
KENIFQMARS QQRDVAT
//
