ID G7MNJ0_MACMU Unreviewed; 786 AA.
AC G7MNJ0;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=Dipeptidyl aminopeptidase-like protein 6 {ECO:0000256|ARBA:ARBA00040948};
DE AltName: Full=Dipeptidyl peptidase 6 {ECO:0000256|ARBA:ARBA00042016};
DE AltName: Full=Dipeptidyl peptidase VI {ECO:0000256|ARBA:ARBA00041991};
DE Flags: Fragment;
GN ORFNames=EGK_14372 {ECO:0000313|EMBL:EHH17888.1};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|EMBL:EHH17888.1};
RN [1] {ECO:0000313|EMBL:EHH17888.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CR-5 {ECO:0000313|EMBL:EHH17888.1};
RX PubMed=22002653; DOI=10.1038/nbt.1992;
RA Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT "Genome sequencing and comparison of two nonhuman primate animal models,
RT the cynomolgus and Chinese rhesus macaques.";
RL Nat. Biotechnol. 29:1019-1023(2011).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM001255; EHH17888.1; -; Genomic_DNA.
DR AlphaFoldDB; G7MNJ0; -.
DR MEROPS; S09.973; -.
DR Proteomes; UP000013456; Chromosome 3.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 2.140.10.30; Dipeptidylpeptidase IV, N-terminal domain; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR001375; Peptidase_S9.
DR InterPro; IPR002469; Peptidase_S9B_N.
DR PANTHER; PTHR11731:SF20; DIPEPTIDYL AMINOPEPTIDASE-LIKE PROTEIN 6; 1.
DR PANTHER; PTHR11731; PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED; 1.
DR Pfam; PF00930; DPPIV_N; 1.
DR Pfam; PF00326; Peptidase_S9; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF82171; DPP6 N-terminal domain-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 15..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 114..482
FT /note="Dipeptidylpeptidase IV N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00930"
FT DOMAIN 563..769
FT /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT /evidence="ECO:0000259|Pfam:PF00326"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EHH17888.1"
FT NON_TER 786
FT /evidence="ECO:0000313|EMBL:EHH17888.1"
SQ SEQUENCE 786 AA; 89556 MW; E42F38B61975D047 CRC64;
ELVGSNPPQR NWKGIAIALL VILVICSLIV TSVILLTPAE DNSLSQKKKV TVEDLFSEDF
KIHDPEAKWI SDTEFIYREQ KGTVRLWNVE TNTSTVLIEG KKIESLRAIK YEISPDREYA
LFSYNVEPIY QHSYSGYYVL SKIPHGDPQS LDPPEVSNAK LQYAGWGPKG QQLIFIFENN
IYYCAHVGKQ AIRVVSTGKE GVIYNGLSDW LYEEEILKTH IAHWWSPDGT RLAYATINDS
RVPLMELPTY TGSVYPTVKP YHYPKAGSEN PSISLHVIGL NGPTHDLEMM PPDDPRMREY
YITMVKWATS TKVAVTWLNR AKKKNVSILT LCDATTGVCT KKHEDESEAW LHRQNEEPVF
SKDGRKFFFI RAIPQGGRGK FYHITVSSSQ PNSSNDNIQS ITSGDWDVTK ILAYDEKGNK
IYFLSTEDLP RRRQLYSANT VGNFNRQCLS CDLVENCTYF SASFSHSMDF FLLKCEGPGI
PMVTVHNTTD KKKIFDLETN EHVKKAINDR QMPKVEYRNI EIDDYNLPMQ ILKPATFTDT
THYPLLLVVD GTPGSQSVSE KFEVSWETVM VSSHGAVVVK CDGRGSGFQG TKLLHEVRRR
LGLLEEKDQM EAVRTMLKEQ YIDRTRVAVF GKDYGGYLST YILPAKGENQ GQTFTCGSAL
SPITDFKLYA SAFSERYLGL HGLDNRAYEM TKVAHRVSAL EEQQFLIIHP TADEKIHFQH
TAELITQLIR GKANYSLQIY PDESHYFHSA SLKQHLYRSI INFFVECFRI QDKLPTVTAK
EDEEDD
//
