ID G7MZL1_MACMU Unreviewed; 137 AA.
AC G7MZL1;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 22-FEB-2023, entry version 29.
DE RecName: Full=Protein phosphatase 1 regulatory subunit 14 {ECO:0000256|RuleBase:RU369059};
DE Flags: Fragment;
GN ORFNames=EGK_19057 {ECO:0000313|EMBL:EHH28587.1};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|EMBL:EHH28587.1};
RN [1] {ECO:0000313|EMBL:EHH28587.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CR-5 {ECO:0000313|EMBL:EHH28587.1};
RX PubMed=22002653; DOI=10.1038/nbt.1992;
RA Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT "Genome sequencing and comparison of two nonhuman primate animal models,
RT the cynomolgus and Chinese rhesus macaques.";
RL Nat. Biotechnol. 29:1019-1023(2011).
CC -!- FUNCTION: Inhibitor of PPP1CA. {ECO:0000256|RuleBase:RU369059}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|RuleBase:RU369059}.
CC -!- SIMILARITY: Belongs to the PP1 inhibitor family.
CC {ECO:0000256|ARBA:ARBA00005483, ECO:0000256|RuleBase:RU369059}.
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DR EMBL; CM001260; EHH28587.1; -; Genomic_DNA.
DR AlphaFoldDB; G7MZL1; -.
DR Proteomes; UP000013456; Chromosome 8.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.
DR GO; GO:0042325; P:regulation of phosphorylation; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.150.220; CPI-17; 1.
DR InterPro; IPR008025; CPI-17.
DR InterPro; IPR036658; CPI-17_sf.
DR PANTHER; PTHR16188; PROTEIN PHOSPHATASE 1 INHIBITOR POTENTIATED BY PROTEIN KINASE C; 1.
DR PANTHER; PTHR16188:SF5; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 14B; 1.
DR Pfam; PF05361; PP1_inhibitor; 1.
DR SUPFAM; SSF81790; Myosin phosphatase inhibitor 17kDa protein, CPI-17; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|RuleBase:RU369059};
KW Phosphoprotein {ECO:0000256|RuleBase:RU369059};
KW Protein phosphatase inhibitor {ECO:0000256|ARBA:ARBA00023272,
KW ECO:0000256|RuleBase:RU369059}.
FT REGION 1..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 66..93
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EHH28587.1"
FT NON_TER 137
FT /evidence="ECO:0000313|EMBL:EHH28587.1"
SQ SEQUENCE 137 AA; 15183 MW; A06B68E79468000B CRC64;
ALAAPAPGLG SGGPGPRVYF QSPPGTAGEG PSGADDEGPV RRQGKVTVKY DRKELRKRLN
LEEWIQEQLT RLYDCQEEEI PELEIDVDEL LDMESDDARA ARVKELLVDC YKPTEAFISG
LLDKIRGMQK LSTPQKK
//
