ID   G7N389_MACMU            Unreviewed;       598 AA.
AC   G7N389;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   RecName: Full=Cell division cycle 45 {ECO:0008006|Google:ProtNLM};
GN   ORFNames=EGK_02786 {ECO:0000313|EMBL:EHH20021.1};
OS   Macaca mulatta (Rhesus macaque).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9544 {ECO:0000313|EMBL:EHH20021.1};
RN   [1] {ECO:0000313|EMBL:EHH20021.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CR-5 {ECO:0000313|EMBL:EHH20021.1};
RX   PubMed=22002653; DOI=10.1038/nbt.1992;
RA   Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA   Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA   Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA   Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA   Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA   Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT   "Genome sequencing and comparison of two nonhuman primate animal models,
RT   the cynomolgus and Chinese rhesus macaques.";
RL   Nat. Biotechnol. 29:1019-1023(2011).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the CDC45 family.
CC       {ECO:0000256|ARBA:ARBA00010727}.
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DR   EMBL; CM001262; EHH20021.1; -; Genomic_DNA.
DR   AlphaFoldDB; G7N389; -.
DR   Proteomes; UP000013456; Chromosome 10.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   InterPro; IPR003874; CDC45.
DR   PANTHER; PTHR10507; CDC45-RELATED PROTEIN; 1.
DR   PANTHER; PTHR10507:SF0; CELL DIVISION CONTROL PROTEIN 45 HOMOLOG; 1.
DR   Pfam; PF02724; CDC45; 1.
PE   3: Inferred from homology;
KW   Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW   DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT   REGION          136..211
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        147..182
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   598 AA;  68857 MW;  6FA47A78B29D17ED CRC64;
     MFVSDFRKEF YEVVQSQRVL LFVASDVDAL CACKILQALF QCDHVQYTLV PVSGWQELET
     SFLEHKEQFR HFILINCGAN VDLLDILQPD EDTIFFVCDT HRPVNVINVY NNTQIKLLIK
     QDDDLEVPAY EDIFRDEEED EEHSGNDSDG SEPSEKRTRL EEEIVEETMR RRQRREWEAR
     SGSESEPVAA ALEKSSRLFP GPMSDRTAPR SPRRDILFDY EQYEYHGTSS AMVMFELAWM
     LSKDLNDMLW WAIVGLTDQW VQDKITQMKY VTDVGVLQRH VSRHNHRNED EENTLSVDCT
     RISFEYDLRL ALYQHWSLHD SLCNTSYTAA RFKLWSVHGQ KRLQEFLADM GLPLKQVKQK
     FQAMDISLKE NLREMIEESA NKFGMKDMRV QTFSIHFGFK HKFLASDVVF ATMSLMESPE
     RDGSGTDHFI QALDSLSRSN LDKLYHGLEL AKKQLRATQQ TIASCLCTNL VISQGPFLYC
     SLMEGTPDVM LFSRPASLSL LSKHLLKSFV CSTKNRRCKL LPLVMAAPLS VEHGTVTVVG
     IPPETDSSDR KNFFGRAFEK AAESTSSRML HNHFDLSVIE LKAEDRSKFL DALISLLS
//