ID G7N726_MACMU Unreviewed; 540 AA.
AC G7N726;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Cytokeratin-73 {ECO:0000313|EMBL:EHH20761.1};
GN ORFNames=EGK_03683 {ECO:0000313|EMBL:EHH20761.1};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|EMBL:EHH20761.1};
RN [1] {ECO:0000313|EMBL:EHH20761.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CR-5 {ECO:0000313|EMBL:EHH20761.1};
RX PubMed=22002653; DOI=10.1038/nbt.1992;
RA Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT "Genome sequencing and comparison of two nonhuman primate animal models,
RT the cynomolgus and Chinese rhesus macaques.";
RL Nat. Biotechnol. 29:1019-1023(2011).
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR EMBL; CM001263; EHH20761.1; -; Genomic_DNA.
DR AlphaFoldDB; G7N726; -.
DR Proteomes; UP000013456; Chromosome 11.
DR GO; GO:0005829; C:cytosol; IEA:UniProt.
DR GO; GO:0045095; C:keratin filament; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR032444; Keratin_2_head.
DR InterPro; IPR003054; Keratin_II.
DR PANTHER; PTHR45616; GATA-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45616:SF31; KERATIN, TYPE II CYTOSKELETAL 73; 1.
DR Pfam; PF00038; Filament; 1.
DR Pfam; PF16208; Keratin_2_head; 1.
DR PRINTS; PR01276; TYPE2KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 3.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685}; Keratin {ECO:0000256|ARBA:ARBA00022744}.
FT DOMAIN 132..445
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 505..540
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 201..235
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 343..423
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 518..540
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 540 AA; 58987 MW; 81B831A700C35244 CRC64;
MSRQFTYKSG AAAKGGFSGC SAVLSGGSSS SYQAGGKGLS GGFSSRSLYS LGVARSISFN
VASGSGWAGG YGFGRGRASG FAGSMFGSVA LGSVSPSVCP PGGIHQVTIN KSLLAPLNVE
LDPEIQKVRA QEREQIKVLN NKFASFIDKV RFLEQQNQVL ETKWELLQQL DLNNCKNNLE
PILEGYISNL RKQLETLCGD RVRLDSELRS VREVVEDYKK RYEEEINKRT TAENEFVVLK
KDVDAAYMSK VELQAKVDAL DGEIKFFKCL YEGEIAQIQS HISDTSIILS MDNNRNLDLD
SIIAEVRAQY EEIARKSKAE AEALYQTKFQ ELQLAAGQHG DDLKHTKNEI SELTRLIQRL
RSEIESVKKQ CANLETAIAD TEQRGDCALK DARAKLDELE GALHQAKEEL ARMLREYQEL
LSVKLSLDIE IATYRKLLEG EECRMSGEYT NSVSISVINS SMAGTAGARA GFGFSNAGTY
GYWPSSVSGG YSMLPGGCVT GSGNCSPRGE ARTRLGSASE FKDSQGKTLA LSSPTKKTMR
//
