ID   G7NEY7_MACMU            Unreviewed;      1028 AA.
AC   G7NEY7;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   SubName: Full=Prostate antigen recognized and identified by SEREX 1 {ECO:0000313|EMBL:EHH23937.1};
GN   ORFNames=EGK_07509 {ECO:0000313|EMBL:EHH23937.1};
OS   Macaca mulatta (Rhesus macaque).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9544 {ECO:0000313|EMBL:EHH23937.1};
RN   [1] {ECO:0000313|EMBL:EHH23937.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CR-5 {ECO:0000313|EMBL:EHH23937.1};
RX   PubMed=22002653; DOI=10.1038/nbt.1992;
RA   Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA   Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA   Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA   Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA   Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA   Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT   "Genome sequencing and comparison of two nonhuman primate animal models,
RT   the cynomolgus and Chinese rhesus macaques.";
RL   Nat. Biotechnol. 29:1019-1023(2011).
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DR   EMBL; CM001267; EHH23937.1; -; Genomic_DNA.
DR   AlphaFoldDB; G7NEY7; -.
DR   Proteomes; UP000013456; Chromosome 15.
DR   CDD; cd01265; PH_TBC1D2A; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   Gene3D; 1.10.8.270; putative rabgap domain of human tbc1 domain family member 14 like domains; 1.
DR   Gene3D; 1.10.472.80; Ypt/Rab-GAP domain of gyp1p, domain 3; 1.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR000195; Rab-GAP-TBC_dom.
DR   InterPro; IPR035969; Rab-GAP_TBC_sf.
DR   PANTHER; PTHR47219; RAB GTPASE-ACTIVATING PROTEIN 1-LIKE; 1.
DR   PANTHER; PTHR47219:SF16; TBC1 DOMAIN FAMILY MEMBER 2B; 1.
DR   Pfam; PF00169; PH; 1.
DR   Pfam; PF00566; RabGAP-TBC; 1.
DR   SMART; SM00233; PH; 1.
DR   SMART; SM00164; TBC; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   SUPFAM; SSF47923; Ypt/Rab-GAP domain of gyp1p; 2.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
DR   PROSITE; PS50086; TBC_RABGAP; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}.
FT   DOMAIN          101..198
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   DOMAIN          696..888
FT                   /note="Rab-GAP TBC"
FT                   /evidence="ECO:0000259|PROSITE:PS50086"
FT   REGION          1..91
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          282..331
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          357..452
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          503..530
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          946..980
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        11..25
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1028 AA;  116817 MW;  7C42067B893B1EA6 CRC64;
     MDGIGLRSPN GETRLRKEGE KFKGKQVSPF GKLPAESPRF VPGGPVDSSS LRGLRLAAME
     GAGENAPESS SSVPGSDESA RDPQALPLEE ESGDCARSLE AKKLCGYLSK FGGKGPIRGW
     KSRWFFYDER KCQLYYSRTA QDANPLDSID LSSAVFDCKA DGEEGIFEIK TPSRVMTLKA
     ATKQVMLYWL QQLQMKRWEF HNSPPAPPAA PDAALAGNGP ALHLELGQEE AELEEFLCPV
     KTPPGLVGVA AALQPFPALQ NISLKHLGTE IQNTMHNIRG NKQAQATGHE PPGEDSPQSG
     EPQREEQPLA SDPTTPGREP EDSPKPGPKS SLTISFVQKA KRQNNTFPFF SEGITWNRTA
     QEKVAALEQQ VLMLTKELKS QKELVKILHK ALEAAQQEKR ASSAYLAAAE DKDRLELVRH
     KVRQIAELGR RVEALEQERE SLAHTASLRE QEVQELQQHV QLLMDKNHAK QQVICKLSEK
     VTQDFTQPPD QSPLPPDAAD RDFLSQQEKI EHLKDDMEAY RTQNRFLNSE IHQVTKIWRK
     VAEKEKALLT KCAYLQARNC QVESKYLAGL RRLQEALGDE TSECSELLRQ LVQEALQWEA
     GEASSDSIEL SPIREGFCKV LLTWTFAGSK YDEYGFLTVP DYEVEDLKLL AKIQALEVRS
     HHLLGLEAVD RPLRERWAAL GELVPSAELK QLLRAGVPRE HRPRVWRWLV HLRVQHLHTP
     GCYQELLSRG RAREHPAARQ IELDLNRTFP NNKHFTCPTS SFPDKLRRVL LAFSWQNPTI
     GYCQGLNRLA AIALLVLEEE ESAFWCLVAI VETIMPTDYY SNTLTASQVD QRVLQDLLSE
     KLPRLMAHLG QHHVDLSLIT FNWFLVVFAD SLISNILLRV WDAFLYEGTK VVFRYALAVF
     KYNEKEILRL HNGLEIYQYL RFFTKTISNS RKLMNIAFND MNPFRMKQLQ QLRMVHRERL
     EAELRELEQL KAEYMERRTS QHRAMSDGCA SEDELYIECL LCATEQFKAL KITVFTEQNQ
     ELFGDVVW
//