ID G7NFT5_MACMU Unreviewed; 327 AA.
AC G7NFT5;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Nuclear apoptosis-inducing factor 1 {ECO:0000256|ARBA:ARBA00014166};
GN ORFNames=EGK_07328 {ECO:0000313|EMBL:EHH23784.1};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|EMBL:EHH23784.1};
RN [1] {ECO:0000313|EMBL:EHH23784.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CR-5 {ECO:0000313|EMBL:EHH23784.1};
RX PubMed=22002653; DOI=10.1038/nbt.1992;
RA Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT "Genome sequencing and comparison of two nonhuman primate animal models,
RT the cynomolgus and Chinese rhesus macaques.";
RL Nat. Biotechnol. 29:1019-1023(2011).
CC -!- FUNCTION: Induces apoptosis. {ECO:0000256|ARBA:ARBA00003564}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the NAIF1 family.
CC {ECO:0000256|ARBA:ARBA00010629}.
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DR EMBL; CM001267; EHH23784.1; -; Genomic_DNA.
DR AlphaFoldDB; G7NFT5; -.
DR Proteomes; UP000013456; Chromosome 15.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR InterPro; IPR028002; Myb_DNA-bind_5.
DR PANTHER; PTHR23098; AGAP001331-PA-RELATED; 1.
DR PANTHER; PTHR23098:SF7; NUCLEAR APOPTOSIS-INDUCING FACTOR 1; 1.
DR Pfam; PF13873; Myb_DNA-bind_5; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT DOMAIN 8..85
FT /note="Myb/SANT-like DNA-binding"
FT /evidence="ECO:0000259|Pfam:PF13873"
FT REGION 87..119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 303..327
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 327 AA; 35168 MW; A8D5B7F2367E05B2 CRC64;
MAVPAKKRKM NFSEREVEII VEELELKKHL LVNHFNAGLP LAAKSAAWHG ILRRVNAVAT
CRRELPEVKK KWSDLKTEVR RKVAQVRAAV EGGEAPGSTE EDGAGGPGTG GGSGGGGPAV
APVLLTPMQQ RICNLLGEAT IISLPSTTEI HPVALGPSAT AAAATVTLTQ IPTETTYHTL
EEGVVEYCTA EAPPPLPPEA PVDMMAQHAD TSVKPQALKS RIALNSAKLI QEQRVTNLHV
KEIAQHLEQQ NDLLQMIRRS QEVQACAQER QAQAMEGTQA ALSVLIQVLR PMIKDFRRYL
QSNTANPAPT SDPGQVAQNG QPDSIIQ
//
