ID G7NHX9_MACMU Unreviewed; 1497 AA.
AC G7NHX9;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011};
GN ORFNames=EGK_08585 {ECO:0000313|EMBL:EHH24858.1};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|EMBL:EHH24858.1};
RN [1] {ECO:0000313|EMBL:EHH24858.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CR-5 {ECO:0000313|EMBL:EHH24858.1};
RX PubMed=22002653; DOI=10.1038/nbt.1992;
RA Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT "Genome sequencing and comparison of two nonhuman primate animal models,
RT the cynomolgus and Chinese rhesus macaques.";
RL Nat. Biotechnol. 29:1019-1023(2011).
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DR EMBL; CM001268; EHH24858.1; -; Genomic_DNA.
DR Proteomes; UP000013456; Chromosome 16.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0008608; P:attachment of spindle microtubules to kinetochore; IEA:InterPro.
DR GO; GO:0043063; P:intercellular bridge organization; IEA:InterPro.
DR GO; GO:0007140; P:male meiotic nuclear division; IEA:InterPro.
DR GO; GO:0051306; P:mitotic sister chromatid separation; IEA:InterPro.
DR GO; GO:0007094; P:mitotic spindle assembly checkpoint signaling; IEA:InterPro.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR039339; Tex14.
DR PANTHER; PTHR23060:SF1; INACTIVE SERINE_THREONINE-PROTEIN KINASE TEX14; 1.
DR PANTHER; PTHR23060; TESTIS EXPRESSED GENE 14; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR SMART; SM00248; ANK; 3.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 2.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Coiled coil {ECO:0000256|SAM:Coils}.
FT REPEAT 55..87
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 88..120
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 242..518
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 837..877
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 946..1048
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1146..1166
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1347..1470
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 747..774
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 952..966
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 988..1003
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1152..1166
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1347..1365
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1367..1470
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1497 AA; 168188 MW; 3C2C8357A9FA0AE7 CRC64;
MSRAVPLPLP CPVQLGTLRN DSLEAQLHEY VKQGNYLKVK KILKKGIYVD AVNNLGQTAL
FVAALLGLRK LVDVLVDYGS DPNHRCFDGS TPVHAAAFSG NQWILSKLLD AGGDLRLHDE
RGQNPKTWAL TAGKERSTQI VEFMQRCALH MQAIIQGFSY DLLKKIDSPQ RLVYSPPWFG
SLVQGNPNGS PNRLLKAGVI SAQNIYSFGF GKAMPWFQFY LTGATQIAYL GSLLVIGEKE
VIQADDEPTF SFFSGPYMVM TNLVWNGSRV TVKELNLPTH PHCSKLRLAD LLIAEQEHSS
KLRHPYLLQL MAVCLSQDLE KTRLVYERIT IGTLFSVLHE RRSQFPVLHM EVIVHLLLQI
SDALRYLHSQ GFIHRSLSSY AVHIVSPGEA RLTNLEYMLE SKDRGEQRDL TRVPLPTQLY
NWAAPEVILQ KAATVKSDIY SFSMIIQEIL TDDIPWNGLD GSVIKEAIVL GNYLEADVRL
PKPYYDIVKL GIHIKQKDRT MNLQDIRYIL KNDLKDFTGT QRTQPTESPR VQRYGLHPDV
NVYLGLTSEH TRETPDMEII ELKEMGSQPH SPRVHSLFTE GTLDPQAPDP CLMARETQNQ
DAPCPTPFMA EEASSPSTGQ ASLCSFEINE IYSGCLTLED DIEEPPGAAS SLEADGPNQV
DELQSMEEEL DKMEREACCF CSEDESSSKA ETEYSFEDWD WQNGSLSSLS LPESTREAKS
NLNNRSMAEE YLISKCVLDL KIMQTIMHEN DDRLRNIEQI LDEVEMKQKE QEERMSLWAT
SREFTDVYNL PPAVGPPSLN YIPPVLQLSG GQQPDTSGKC PTLPRFPRML LTLCDPGKQN
TDEQFQGTQG VKDSLERSRI QNTSSRGKPR ESTAQAKATQ FDSALFTLSS HWQGPSASPN
SHWDSTRMSV DPVSSEIYNA ESRNKDDGEV HLKWKMEVKE MAEKAATGQL TVPPWHPQSS
LTLESEAENE PDALLQPPIG SPENTDWQRV IEYHRENDEP RGNAKFDNTG NNDCDSDQHD
RQPRPGSFTN IRHPSPRQKE QPEYSEAFQA SSDALVAVEK SYSHQSMQST CSPESSEDIT
DEFLTPDDEY FYSSTAQENL ALETSSPIEE EFEGIQGAFA QPQVSGEEKF QMRKILGKNA
EILPRSQFQP IRSTEDEQEE TSKESLKELK EKDISLTDIQ DLSSISYEPD SSFKEASCRT
PRINHAPTSV STPLSPGSVS SAASQYKDCI ESITFQVKTE SASCWNSQEF IQTLSDEFIS
VRERAKKLDS LLTASETCPS RLPGLKRLSS FIGAGSSSLV KACDSSPPHA TQRRSLPKVE
AFSQHHIDEL PPPSQELLDE IELLKQQQGS STVLHENTAS DAGGTANDQR HLEEQETDSK
KEDSSMLLSK ETGDLGEDTE RAHSTLDEDL ERWLQPPEES MKLQDLPKGS EREINIKDQE
VGEDKRKRED SITPERRKSE SVLGTSEEDE LKPCFWKRLG WSESSRIIVL DQSDLSD
//
